CAS No. 109552-15-0
Chemical Structure
Check the
Pamidronate disodium pentahydrate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | disodium;[3-amino-1-hydroxy-1-[hydroxy(oxido)phosphoryl]propyl]-hydroxyphosphinate;pentahydrate | |
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| CAS Number | 109552-15-0 | |
| Molecular Formula |
C3H11NO7P2.5H2O.2Na |
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| Molecular Weight (MW) | 371.13 | |
| InChIKey | CZYWHNTUXNGDGR-UHFFFAOYSA-L |
Pamidronate disodium pentahydrate is a nitrogen-containing bisphosphonate that acts as a potent inhibitor of farnesyl pyrophosphate synthase. By disrupting the mevalonate pathway, it impairs protein prenylation, suppressing osteoclast activity and osteoclast-mediated bone resorption. Additionally, it modulates key signaling cascades involved in bone homeostasis, preventing bone loss and preserving bone mineral density.
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- Pamidronate disodium pentahydrate Solubility in DMSO
- Pamidronate disodium pentahydrate Stock Solution
- Pamidronate disodium pentahydrate Storage
- Pamidronate disodium pentahydrate Stability
- Pamidronate disodium pentahydrate Molecular Weight
- Pamidronate disodium pentahydrate Chemical Structure (2D and 3D)
- Pamidronate disodium pentahydrate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.