CAS No. 1235481-90-9
| IUPAC Name | N-[3-(3,6-dibromocarbazol-9-yl)-2-fluoropropyl]-3-methoxyaniline | |
|---|---|---|
| CAS Number | 1235481-90-9 | |
| Molecular Formula |
C22H19Br2FN2O |
|
| Molecular Weight (MW) | 506.21 | |
| SMILES | COC1=CC=CC(=C1)NCC(CN2C3=C(C=C(C=C3)Br)C4=C2C=CC(=C4)Br)F | |
| InChIKey | XNLTWMQBJFWQOU-UHFFFAOYSA-N |
P7C3-A20 is a proneurogenic aminopropyl carbazole compound that acts as an activator of nicotinamide phosphoribosyltransferase (NAMPT). By activating NAMPT, P7C3-A20 helps maintain intracellular NAD+ levels, thereby preventing neuronal cell death and promoting adult neurogenesis. This neuroprotective activity enhances endogenous brain repair mechanisms and preserves cognitive and motor functions following traumatic brain injury and in neurodegenerative disease models. [1]
|
Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(197.54 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(197.54 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | ˂1 mg/mL |
| Ethanol | ˂1 mg/mL |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.