CAS No. 123-08-0
Batch:
Purity:99.99
Chemical Structure
Check the
p-Hydroxybenzaldehyde
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 123-08-0 | |
|---|---|---|
| Molecular Formula |
C7H6O2 |
|
| Molecular Weight (MW) | 122.12 | |
| SMILES | C1=CC(=CC=C1C=O)O |
p-Hydroxybenzaldehyde is a naturally occurring hydroxybenzaldehyde derivative that acts as a modulator of GABAA receptors. At a concentration of, it significantly reduces GABA-induced chloride currents in GABAA receptors of the α1β2γ2S subtype. By modulating chloride ion flux through GABAA receptor channels, p-hydroxybenzaldehyde influences GABAergic signaling pathways and downstream neuronal excitability. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
24 mg/mL
(196.52 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.