CAS No. 189224-26-8
Batch:
Purity:99.98
Chemical Structure
Check the
Ozagrel sodium
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | sodium (E)-3-[4-(imidazol-1-ylmethyl)phenyl]prop-2-enoate | |
|---|---|---|
| CAS Number | 189224-26-8 | |
| Molecular Formula |
C13H11N2O2.Na |
|
| Molecular Weight (MW) | 250.23 | |
| SMILES | C1=CC(=CC=C1CN2C=CN=C2)C=CC(=O)[O-].[Na+] | |
| InChIKey | NCNYJCOBUTXCBR-IPZCTEOASA-M |
Biological Activity
Ozagrel sodium is a potent thromboxane A2 synthase (CYP5) inhibitor that possesses neuroprotective properties. By inhibiting thromboxane A2 synthase, it reduces the synthesis of thromboxane A2, leading to the inhibition of platelet aggregation and promotion of vasodilation. Consequently, ozagrel sodium exerts protective downstream effects against ischemic neuronal damage and microvascular thrombosis in cerebral ischemia models.
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 50 mg/mL |
| DMSO |
1 mg/mL
(3.99 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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Note: Technical data last updated: Sep 1, 2026.