CAS No. 59-48-3
Batch:
Purity:99.36
Chemical Structure
Check the
Oxindole
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 1,3-dihydroindol-2-one | |
|---|---|---|
| CAS Number | 59-48-3 | |
| Molecular Formula |
C8H7NO |
|
| Molecular Weight (MW) | 133.15 | |
| SMILES | C1C2=CC=CC=C2NC1=O | |
| InChIKey | JYGFTBXVXVMTGB-UHFFFAOYSA-N |
Oxindole is an aromatic heterocyclic organic compound and endogenous tryptophan metabolite with diverse biological activities. At elevated concentrations, oxindole impairs central nervous system function, leading to sedation, muscle weakness, hypotension, and loss of consciousness. Furthermore, oxindole serves as a key pharmacophore in medicinal chemistry, exhibiting anticancer, antibacterial, antiviral, and antidiabetic properties through the modulation of multiple cellular pathways. [1][2]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
26 mg/mL
(195.26 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.