CAS No. 20559-55-1
Batch:
Purity:99.58
Chemical Structure
Check the
Oxibendazole
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | methyl N-(6-propoxy-1H-benzimidazol-2-yl)carbamate | |
|---|---|---|
| CAS Number | 20559-55-1 | |
| Molecular Formula |
C12H15N3O3 |
|
| Molecular Weight (MW) | 249.27 | |
| SMILES | CCCOC1=CC2=C(C=C1)N=C(N2)NC(=O)OC | |
| InChIKey | RAOCRURYZCVHMG-UHFFFAOYSA-N |
Oxibendazole is a broad-spectrum benzimidazole anthelmintic agent that targets parasite tubulin. By selectively binding to β-tubulin, oxibendazole inhibits tubulin polymerization and disrupts microtubule dynamics within helminthic cells. This disruption impairs essential microtubule-dependent cellular functions, including glucose transport and energy metabolism, ultimately leading to metabolic starvation and antiparasitic activity against various intestinal roundworms and nematodes.
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
3 mg/mL
(12.03 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| 4-Methylpyridine | 4 mg/mL |
| DMSO |
1 mg/mL
(4.01 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.