Oxaliplatin is a potent DNA cross-linker. It affects DDR and p53 signaling by forming Pt-DNA adducts, promoting apoptosis.
Comprehensive IC50 Values for Oxaliplatin Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.
Oxaliplatin is a potent DNA cross-linker. It affects DDR and p53 signaling by forming Pt-DNA adducts, promoting apoptosis.