CAS No. 1173-88-2

Batch: Purity:99.69
Oxacillin sodium Chemical Structure
Chemical Structure
Check the Oxacillin sodium product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name sodium (2S,5R,6R)-3,3-dimethyl-6-[(5-methyl-3-phenyl-1,2-oxazole-4-carbonyl)amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
CAS Number 1173-88-2
Molecular Formula

C19H18N3NaO5S

Molecular Weight (MW) 423.42
SMILES [Na+].CC1=C(C(=O)NC2C3SC(C)(C)C(N3C2=O)C([O-])=O)C(=NO1)C4=CC=CC=C4
InChIKey VDUVBBMAXXHEQP-SLINCCQESA-M

Ordering Information

Biological Activity

Oxacillin sodium is a narrow-spectrum β-lactam antibiotic that targets penicillin-binding proteins (PBPs) involved in bacterial cell wall synthesis. By binding to PBPs, oxacillin inhibits the transpeptidase-catalyzed cross-linking of peptidoglycan chains within the bacterial cell wall, compromising structural integrity and leading to osmotic cell lysis in sensitive strains such as Staphylococcus aureus. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 85 mg/mL (200.74 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 85 mg/mL
Ethanol 8 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.