CAS No. 187227-45-8
Batch:
Purity:99.01
Chemical Structure
Check the
Oseltamivir acid
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (3R,4R,5S)-4-acetamido-5-amino-3-pentan-3-yloxycyclohexene-1-carboxylic acid | |
|---|---|---|
| CAS Number | 187227-45-8 | |
| Molecular Formula |
C14H24N2O4 |
|
| Molecular Weight (MW) | 284.35 | |
| InChIKey | NENPYTRHICXVCS-YNEHKIRRSA-N |
Oseltamivir acid (GS 4071) is a metabolite of oseltamivir that acts as a competitive inhibitor of influenza neuraminidases A and B. By selectively inhibiting viral neuraminidase enzymatic activity, it blocks the cleavage of terminal sialic acid residues on host cell receptors. This inhibition prevents progeny virus budding and release from infected cells, thereby suppressing viral replication and spreading. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 57 mg/mL |
| Ethanol | 14 mg/mL |
| DMSO |
6 mg/mL
(21.1 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.