CAS No. 341-69-5
Batch:
Purity:98
Chemical Structure
Check the
Orphenadrine Hydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 341-69-5 | |
|---|---|---|
| Molecular Formula |
C18H24ClNO |
|
| Molecular Weight (MW) | 305.84 | |
| SMILES | CC1=CC=CC=C1C(C2=CC=CC=C2)OCCN(C)C.Cl |
Orphenadrine Hydrochloride is an uncompetitive NMDA receptor antagonist, histamine H1 receptor antagonist, and nonselective muscarinic acetylcholine receptor (mAChR) antagonist. It modulates central neurotransmitter pathways by blocking ionotropic glutamate receptor ion channels and muscarinic signaling cascades. This target inhibition attenuates excitatory postsynaptic neurotransmission and downstream cholinergic activity, promoting centrally mediated muscle relaxant phenotypes. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
61 mg/mL
(199.45 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Orphenadrine Hydrochloride Solubility in DMSO
- Orphenadrine Hydrochloride Stock Solution
- Orphenadrine Hydrochloride Storage
- Orphenadrine Hydrochloride Stability
- Orphenadrine Hydrochloride Molecular Weight
- Orphenadrine Hydrochloride SMILES
- Orphenadrine Hydrochloride Chemical Structure (2D and 3D)
- Orphenadrine Hydrochloride SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.