CAS No. 869477-96-3

Batch: Purity:99.87
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Olodaterol hydrochloride Chemical Structure
Chemical Structure
Check the Olodaterol hydrochloride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 869477-96-3
Molecular Formula

C21H27ClN2O5
Molecular Weight (MW) 422.9
SMILES CC(C)(CC1=CC=C(C=C1)OC)NCC(C2=C3C(=CC(=C2)O)NC(=O)CO3)O.Cl

Ordering Information

Biological Activity

Olodaterol hydrochloride is a highly potent, long-acting β2-adrenergic receptor agonist. Activation of the β2-adrenergic receptor stimulates adenylate cyclase activity to elevate intracellular cAMP levels, which subsequently triggers protein kinase A (PKA) signaling and downstream airway smooth muscle relaxation. This compound effectively inhibits contractile responses and modulates pulmonary signaling cascades in preclinical models of airway hyperresponsiveness. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 85 mg/mL (200.99 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 85 mg/mL
Ethanol 85 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.