CAS No. 23696-28-8
Batch:
Purity:99.87
Chemical Structure
Check the
Olaquindox
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 23696-28-8 | |
|---|---|---|
| Molecular Formula |
C12H13N3O4 |
|
| Molecular Weight (MW) | 263.25 | |
| SMILES | CC1=C([N+](=O)C2=CC=CC=C2N1[O-])C(=O)NCCO |
Biological Activity
Olaquindox is an oral quinoxaline 1,4-dioxide derivative that acts as an antibacterial agent and feed additive. It promotes the intracellular generation of reactive oxygen species (ROS), leading to oxidative stress and induction of DNA damage. Downstream cascade activation involves the ROS-mediated mitochondrial apoptotic pathway, resulting in cellular oxidative damage, cell cycle arrest, and apoptosis in susceptible bacterial and mammalian cells.
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
38 mg/mL
(144.34 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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Note: Technical data last updated: Sep 1, 2026.