CAS No. 218282-71-4

Batch: Purity:99.28
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Olanexidine Hydrochloride semihydrate Chemical Structure
Chemical Structure
Check the Olanexidine Hydrochloride semihydrate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 218282-71-4
Molecular Formula

C17H29Cl3N5O0.5
Molecular Weight (MW) 417.8
SMILES CCCCCCCCN=C(N)NC(=NCC1=CC(=C(C=C1)Cl)Cl)N.CCCCCCCCN=C(N)NC(=NCC1=CC(=C(C=C1)Cl)Cl)N.O.Cl.Cl

Ordering Information

Biological Activity

Olanexidine is a monobiguanide compound that acts as a potent bactericidal agent. It exerts broad-spectrum antimicrobial activity by targeting and disrupting bacterial cell membrane integrity, leading to intracellular component leakage and cell lysis. Olanexidine effectively suppresses various Gram-positive and Gram-negative pathogens, including drug-resistant strains such as methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 82 mg/mL (196.26 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 82 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.