CAS No. 1357302-64-7
Batch:
Purity:99.8
Chemical Structure
Check the
OG-L002
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 3-[4-[(1R,2S)-2-aminocyclopropyl]phenyl]phenol | |
|---|---|---|
| CAS Number | 1357302-64-7 | |
| Molecular Formula |
C15H15NO |
|
| Molecular Weight (MW) | 225.29 | |
| SMILES | C1C(C1N)C2=CC=C(C=C2)C3=CC(=CC=C3)O | |
| InChIKey | DSOJSZXQRJGBCW-CABCVRRESA-N |
OG-L002 is a potent and selective inhibitor of lysine-specific demethylase 1 (LSD1). LSD1 functions as a chromatin-modifying enzyme that specifically demethylates mono- and dimethylated histone H3 lysine 4 (H3K4me1/2), regulating epigenetic gene transcription. Pharmacological inhibition of LSD1 leads to increased H3K4 methylation, gene expression changes, and suppression of cell proliferation in cancer models. [1][2]
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
45 mg/mL
(199.74 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 19 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
Note: Technical data last updated: Sep 1, 2026.