CAS No. 130089-98-4
Batch:
Purity:99.73
Chemical Structure
Check the
NQ301
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 2-(4-acetylanilino)-3-chloronaphthalene-1,4-dione | |
|---|---|---|
| CAS Number | 130089-98-4 | |
| Molecular Formula |
C18H12ClNO3 |
|
| Molecular Weight (MW) | 325.75 | |
| SMILES | CC(=O)C1=CC=C(C=C1)NC2=C(C(=O)C3=CC=CC=C3C2=O)Cl | |
| InChIKey | LSQZKIQSQHZVQS-UHFFFAOYSA-N |
NQ301 is a synthetic naphthoquinone derivative that functions as an antiplatelet and antithrombotic agent by targeting thromboxane A2 (TXA2) synthase and the TXA2 receptor. It effectively inhibits TXA2 synthase activity and blocks TXA2 receptor binding in platelets, thereby suppressing downstream signaling pathways to inhibit collagen- and agonist-induced platelet aggregation and prevent vascular thrombus formation.
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
30 mg/mL
(92.09 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.