CAS No. 14383-51-8

Batch: Purity:98
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Nortropine Hydrochloride Chemical Structure
Chemical Structure
Check the Nortropine Hydrochloride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 14383-51-8
Molecular Formula

C7H13NO.HCl
Molecular Weight (MW) 163.65
SMILES C1CC2CC(CC1N2)O.Cl

Biological Activity

Nortropine Hydrochloride is a secondary metabolite derived from tropine-based anticholinergic drugs, such as atropine and benztropine. As a structural derivative of tropane alkaloids, it serves as a key tool for investigating drug metabolism pathways, biotransformation processes, and receptor interactions within cholinergic signaling systems. Modulations of cholinergic receptor signaling affect downstream central nervous system functions, neurotransmitter release, and parasympathetic pathway activity. [1]

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 32 mg/mL (195.53 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Reference

[1] Caulfield MP, et al. Pharmacol Rev. 1998;50(2):279-90.

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Note: Technical data last updated: Sep 1, 2026.