SMILES:
CC1=CN=C(CNCC2(F)CCN(CC2)C(=O)C3=CC(=C(F)C=C3)Cl)N=C1
Chemical Structure
Check the
NLX-101
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (3-chloro-4-fluorophenyl)-[4-fluoro-4-[[(5-methylpyrimidin-2-yl)methylamino]methyl]piperidin-1-yl]methanone | |
|---|---|---|
| CAS Number | 635323-95-4 | |
| Molecular Formula | ||
| SMILES | CC1=CN=C(CNCC2(F)CCN(CC2)C(=O)C3=CC(=C(F)C=C3)Cl)N=C1 | |
| InChIKey | WAAXKNFGOFTGLP-UHFFFAOYSA-N |
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
79 mg/mL
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Ethanol | 79 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.