CAS No. 791840-86-3
Chemical Structure
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NLRP3
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | N-(3-hydroxyphenyl)-2-(4-methoxyphenyl)acetamide | |
|---|---|---|
| CAS Number | 791840-86-3 | |
| Molecular Formula |
C15H15NO3 |
|
| Molecular Weight (MW) | 257.28 | |
| SMILES | O=C(NC1=CC=CC(O)=C1)CC2=CC=C(OC)C=C2 | |
| InChIKey | OTXSEOHBMQFDBM-UHFFFAOYSA-N |
Biological Activity
NLRP3/aim2-in-2 is a potent small-molecule inhibitor targeting NLRP3 and AIM2 inflammasomes. By disrupting inflammasome assembly, it blocks downstream caspase-1 activation, gasdermin D cleavage, and the release of pro-inflammatory cytokines such as IL-1β and IL-18. This inhibition suppresses inflammasome-dependent pyroptotic cell death and attenuates downstream inflammatory cascade pathways involved in immune responses.
How to Prepare Stock Solution?
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Note: Technical data last updated: Sep 1, 2026.