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NF449 octasodium

Cat.No.E8096

NF449 octasodium is a highly potent P2X1 receptor antagonist, with IC50s of 0.28, 0.69, and 120 nM for rP2X1, rP2X1+5, P2X2+3, respectively. This compound is a Gsα-selective G Protein antagonist. It suppresses the rate of GTP[γS] binding to Gsα-s, inhibits the stimulation of adenylyl cyclase activity, and blocks the coupling of β-adrenergic receptors to Gs.
NF449 octasodium Chemical Structure

Chemical Structure

Molecular Weight: 1505.09

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Quality Control

Chemical Information, Storage & Stability

Molecular Weight 1505.09 Formula Storage (From the date of receipt)
CAS No. 627034-85-9 -- Storage of Stock Solutions Solutions are unstable. Prepare fresh or purchase small, pre-packaged sizes. Repackage upon receipt.

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