CAS No. 161973-10-0

Batch: Purity:99.87
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Esomeprazole magnesium Chemical Structure
Chemical Structure
Check the Esomeprazole magnesium product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name magnesium bis(5-methoxy-2-[(S)-(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfinyl]benzimidazol-1-ide)
CAS Number 161973-10-0
Molecular Formula

C34H36MgN6O6S2
Molecular Weight (MW) 713.12
SMILES CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC.CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC.[Mg+2]
InChIKey KWORUUGOSLYAGD-YPPDDXJESA-N

Ordering Information

Biological Activity

Esomeprazole magnesium is a potent proton pump inhibitor that targets gastric H+/K+-ATPase in parietal cells. By inhibiting the enzymatic action of this proton pump, it prevents the exchange of hydrogen ions across the secretory membrane, effectively blocking the final pathway of gastric acid generation and reducing basal and stimulated acid formation in mucosal tissue.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.