CAS No. 95734-82-0

Batch: Purity:99.74
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Nedaplatin Chemical Structure
Chemical Structure
Check the Nedaplatin product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name azane;2-oxidoacetate;platinum(2+)
CAS Number 95734-82-0
Molecular Formula

C2H8N2O3Pt
Molecular Weight (MW) 303.17
SMILES C(C(=O)O)O.N.N.[Pt]
InChIKey GYAVMUDJCHAASE-UHFFFAOYSA-M

Ordering Information

Biological Activity

Nedaplatin is a platinum-based antineoplastic derivative of cisplatin that functions as a DNA-damaging agent. It induces DNA cross-linking to disrupt DNA replication and RNA transcription, ultimately triggering apoptotic cell death and suppressing tumor colony-forming units. Nedaplatin exhibits broad cytotoxic activity across diverse human cancer cell lines, inhibiting cellular proliferation and tumor growth through DNA-damage response pathways.

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 30 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.