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NBD-557

Cat.No.E7783

NBD-557 is a potentially HIV-1 inhibitor.IC50 Value: Target: HIV. This compound is small molecule organic compounds with drug-like properties. It showed potent cell fusion and virus-cell fusion inhibitory activity at low micromolar levels. A systematic study showed that this compound target viral entry by inhibiting the binding of HIV-1 envelope glycoprotein gp120 to the cellular receptor CD4 but did not inhibit reverse transcriptase, integrase, or protease, indicating that they do not target the later stages of the HIV-1 life cycle to inhibit HIV-1 infection. This chemical potent inhibitors of both X4 and R5 viruses tested in CXCR4 and CCR5 expressing cell lines, respectively, indicating that its anti-HIV-1 activity is not dependent on the
NBD-557 Chemical Structure

Chemical Structure

Molecular Weight: 382.30

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Quality Control

Chemical Information, Storage & Stability

Molecular Weight 382.30 Formula Storage (From the date of receipt)
CAS No. 333352-59-3 -- Storage of Stock Solutions Solutions are unstable. Prepare fresh or purchase small, pre-packaged sizes. Repackage upon receipt.

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Mechanism of Action

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