CAS No. 14259-46-2

Batch: Purity:99.92
Narirutin Chemical Structure
Chemical Structure
Check the Narirutin product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 14259-46-2
Molecular Formula

C27H32O14

Molecular Weight (MW) 580.53

Ordering Information

Biological Activity

Narirutin is a natural flavanone and antioxidant abundant in citrus fruits. It suppresses cellular oxidative stress and attenuates inflammatory responses by modulating key signaling cascades, including the NF-kB pathway. Downstream, narirutin reduces the production of pro-inflammatory cytokines and reactive oxygen species, thereby exhibiting protective effects against inflammatory and allergic phenotypes in various cell and tissue models. [1]

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (172.25 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.