CAS No. 73692-50-9
Batch:
Purity:99.87
Chemical Structure
Check the
Naringenin chalcone
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 73692-50-9 | |
|---|---|---|
| Molecular Formula |
C15H12O5 |
|
| Molecular Weight (MW) | 272.25 | |
| SMILES | C1=CC(=CC=C1C=CC(=O)C2=C(C=C(C=C2O)O)O)O |
Biological Activity
Naringenin chalcone is a natural flavonoid and major active component of tomato skin extract with antioxidant, anti-inflammatory, and metabolic regulatory activities. It suppresses inflammatory signaling in adipocytes by inhibiting monocyte chemoattractant protein-1 (MCP-1) production and downregulating pro-inflammatory cytokine secretion. Through modulation of lipid metabolism and inflammatory pathways, naringenin chalcone attenuates adipocyte dysfunction and inflammatory responses in cell models.
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
54 mg/mL
(198.34 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 54 mg/mL |
| Water | Insoluble |
| DMSO |
54 mg/mL
(198.34 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Jump to
Note: Technical data last updated: Sep 1, 2026.