CAS No. 13860-38-3
Chemical Structure
Check the
N1-Methylpseudouridine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 13860-38-3 | |
|---|---|---|
| Molecular Formula |
C10H14N2O6 |
|
| Molecular Weight (MW) | 258.23 |
N1-Methylpseudouridine is a modified uridine nucleoside utilized in synthetic RNA research and mRNA-based therapeutics. Incorporation of N1-methylpseudouridine into mRNA significantly enhances translation capacity relative to unmodified or alternative modified nucleosides. This modification operates by reducing PKR-associated translational repression and increasing ribosome density through beneficial effects on both translation initiation and elongation pathways, leading to robust protein expression. [1][2]
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Note: Technical data last updated: Sep 1, 2026.