CAS No. 36417-86-4
Batch:
Purity:99.00
Chemical Structure
Check the
N-p-trans-Coumaroyltyramine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (E)-3-(4-hydroxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]prop-2-enamide | |
|---|---|---|
| CAS Number | 36417-86-4 | |
| Molecular Formula |
C17H17NO3 |
|
| Molecular Weight (MW) | 283.32 | |
| InChIKey | RXGUTQNKCXHALN-BJMVGYQFSA-N |
N-p-trans-Coumaroyltyramine is a natural phenolic amide that acts as an uncompetitive alpha-glucosidase inhibitor and a dose-dependent acetylcholinesterase inhibitor. By inhibiting intestinal alpha-glucosidase, it prevents the cleavage of complex carbohydrates into monosaccharides, thereby blunting postprandial blood glucose spikes. Additionally, suppressing acetylcholinesterase activity blocks the enzymatic degradation of acetylcholine within synaptic clefts, modulating downstream cholinergic pathway signaling and neuronal function.
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
57 mg/mL
(201.18 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- N-p-trans-Coumaroyltyramine Solubility in DMSO
- N-p-trans-Coumaroyltyramine Stock Solution
- N-p-trans-Coumaroyltyramine Storage
- N-p-trans-Coumaroyltyramine Stability
- N-p-trans-Coumaroyltyramine Molecular Weight
- N-p-trans-Coumaroyltyramine Chemical Structure (2D and 3D)
- N-p-trans-Coumaroyltyramine SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.