CAS No. 3569-99-1

Batch: Purity:99.88
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N-(Hytroxymethy)micotinamide Chemical Structure
Chemical Structure
Check the N-(Hytroxymethy)micotinamide product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name N-(hydroxymethyl)pyridine-3-carboxamide
CAS Number 3569-99-1
Molecular Formula

C7H8N2O2
Molecular Weight (MW) 152.15
SMILES C1=CC(=CN=C1)C(=O)NCO
InChIKey JRFKIOFLCXKVOT-UHFFFAOYSA-N

Ordering Information

Biological Activity

N-(Hydroxymethyl)nicotinamide is a nicotinamide-derived compound that functions as an antimicrobial agent. As a functional analogue of nicotinamide, it modulates essential microbial metabolic pathways to exert therapeutic activity against pathogen growth. Nicotinamide derivatives disrupt microbial cellular homeostasis, attenuate virulence phenotypes, and inhibit key enzymatic targets such as deacetylases to promote pathogen clearance in infectious disease models. [1][2]

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 30 mg/mL (197.17 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.