CAS No. 67605-85-0
Batch:
Purity:99.89
Chemical Structure
Check the
N-Butanoyl-L-homoserine lactone
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 67605-85-0 | |
|---|---|---|
| Molecular Formula |
C8H13NO3 |
|
| Molecular Weight (MW) | 171.19 | |
| SMILES | CCCC(=O)NC1CCOC1=O |
N-Butanoyl-L-homoserine lactone (C4-HSL) is a small diffusible signaling molecule and quorum-sensing autoinducer that targets transcriptional regulators such as RhlR. By mediating population density-dependent quorum-sensing pathways, C4-HSL controls gene expression to regulate cellular metabolism, biofilm formation, and virulence factor synthesis in bacterial systems. Furthermore, C4-HSL serves as a cleavable linker in the synthesis of antibody-drug conjugates.
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
34 mg/mL
(198.6 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 34 mg/mL |
| Ethanol | 34 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- N-Butanoyl-L-homoserine lactone Solubility in DMSO
- N-Butanoyl-L-homoserine lactone Stock Solution
- N-Butanoyl-L-homoserine lactone Storage
- N-Butanoyl-L-homoserine lactone Stability
- N-Butanoyl-L-homoserine lactone Molecular Weight
- N-Butanoyl-L-homoserine lactone SMILES
- N-Butanoyl-L-homoserine lactone Chemical Structure (2D and 3D)
- N-Butanoyl-L-homoserine lactone SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.