Clinical Trials

Numerous clinical trials evaluate N-acetylcysteine across diverse indications, encompassing oncological conditions like ovarian cancer, respiratory disorders such as chronic obstructive pulmonary disease, and hepatic pathologies including steatohepatitis. Ranging from early Phase 1 safety evaluations to Phase 4 post-marketing studies, these trials are sponsored by academic medical centers, government agencies, and industry collaborators. The portfolio reflects varied recruitment statuses, including upcoming protocols, actively recruiting studies, and completed trials.

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT07136987 NOT_YET_RECRUITING
Tuberculosis
Open Source Pharma Foundation
2026-01 PHASE3
NCT06260566 NOT_YET_RECRUITING
Biliary Atresia
Sanjiv Harpavat
2026-10 PHASE1
NCT07543458 NOT_YET_RECRUITING
Dengue; Severe Dengue; Mosquito-Borne Diseases; Vector Borne Diseases; Arbovirus Infections; Flavivirus Infections; RNA Virus Infections; Hemorrhagic Fever
Oxford University Clinical Research Unit, Vietnam
2026-10-01 PHASE3
NCT07464886 RECRUITING
Mild Depression
University of Cincinnati
2026-02-26 PHASE3
NCT07323446 NOT_YET_RECRUITING
Emotional Dysregulation
Massachusetts General Hospital
2027-01-01 EARLY_PHASE1
NCT03999021 ACTIVE_NOT_RECRUITING
Retinitis Pigmentosa
Johns Hopkins University
2019-06-24 PHASE1
NCT07290530 NOT_YET_RECRUITING
Retinitis Pigmentosa (RP); Usher Syndrome
Nacuity Pharmaceuticals, Inc.
2026-12 PHASE3
NCT05537220 ACTIVE_NOT_RECRUITING
Retinitis Pigmentosa
Johns Hopkins University
2023-10-11 PHASE3
NCT07759895 NOT_YET_RECRUITING
Schizoaffecitve Disorder; Schizophrenia and Schizoaffective Disorder; Schizophrenia and Predominant Negative Symptoms
Amit Lotan
2026-09-01 PHASE2
NCT06083480 RECRUITING
Osteoarthritis, Knee; Total Knee Arthroplasty; Chronic Postsurgical Pain
Vanderbilt University Medical Center
2024-12-06 PHASE4
NCT05494398 ENROLLING_BY_INVITATION
Autism Spectrum Disorder
Stanford University
2024-03-12 PHASE2; PHASE3
NCT07737262 NOT_YET_RECRUITING
Aplastic Anemia
Peking University People's Hospital
2026-08-01 PHASE3
NCT04278898 RECRUITING
Autism Spectrum Disorder
Stanford University
2021-02-12 PHASE2
NCT05986318 RECRUITING
Lung Cancer; Interstitial Lung Disease
David Palma
2025-01-07 PHASE2
NCT07409727 RECRUITING
Ventilation Acquired Pneumonia
Cairo University
2026-03-01 PHASE4
NCT05664789 RECRUITING
Autism Spectrum Disorder
Stanford University
2023-04-26 PHASE2; PHASE3
NCT06909799 RECRUITING
Tuberculosis (TB)
The Aurum Institute NPC
2025-04-28
NCT07273071 NOT_YET_RECRUITING
Sepsis; Acute Infection; Severe Infection
Theis S. Itenov
2026-07 PHASE4
NCT07803952 NOT_YET_RECRUITING
SBP - Spontaneous Bacterial Peritonitis
Tanta University
2026-09-10 PHASE1; PHASE2
NCT06546475 NOT_YET_RECRUITING
Psychosis
National Taiwan University Hospital
2024-08-01 PHASE4
NCT03241732 ENROLLING_BY_INVITATION
Chronic Traumatic Brain Injury
Thomas Jefferson University
2017-06-07
NCT03032601 ENROLLING_BY_INVITATION
Multiple Sclerosis
Thomas Jefferson University
2017-01-05
NCT06811675 RECRUITING
Carbon Monoxide Poisoning; Delayed Neurocognitive Sequelae
China Medical University Hospital
2025-03-23 PHASE4
NCT07117630 RECRUITING
Breast Cancer
Fudan University
2025-09-25 PHASE2
NCT04381897 NOT_YET_RECRUITING
Cornelia de Lange Syndrome
Johns Hopkins University
2026-11-01 PHASE2
NCT04374461 ACTIVE_NOT_RECRUITING
Covid-19
Memorial Sloan Kettering Cancer Center
2020-05-01 PHASE2
NCT07156786 NOT_YET_RECRUITING
Kidney Function Issue; Acute Kidney Injury; Cancer (Solid Tumors); Kidney Function Tests; Acetylcysteine Adverse Reaction
Fakultas Kedokteran Universitas Indonesia
2025-09-15 PHASE2; PHASE3
NCT04542161 ACTIVE_NOT_RECRUITING
Chronic Fatigue Syndrome; Myalgic Encephalomyelitis
Weill Medical College of Cornell University
2020-09-01 PHASE2
NCT04440280 RECRUITING
Fuchs Endothelial Corneal Dystrophy
Massachusetts Eye and Ear Infirmary
2020-09-16 PHASE2
NCT06890507 NOT_YET_RECRUITING
Angina Attacks; Non Obstructive Coronary Artery Disease
University of Adelaide
2025-06-01 PHASE2
NCT02750319 ACTIVE_NOT_RECRUITING
Thoracic Surgery; Atrial Fibrillation in High Risk Patients
Memorial Sloan Kettering Cancer Center
2016-04 PHASE3
NCT00775476 ACTIVE_NOT_RECRUITING
Systemic Lupus Erythematosus
State University of New York - Upstate Medical University
2022-05-05 PHASE2
NCT05122559 ACTIVE_NOT_RECRUITING
Multiple Sclerosis; Multiple Sclerosis, Primary Progressive; Multiple Sclerosis, Secondary Progressive
Emmanuelle Waubant, MD PhD
2022-02-16 PHASE2
NCT07227649 NOT_YET_RECRUITING
Carpal Tunnel Surgery; Trigger Finger Disorder; De Quervain Syndrome; Guyon's Canal; Dupuytren Contracture; Morton Neuroma; Tarsal Tunnel Syndrome; Plantar Fasciopathy; Peroneal Nerve Entrapment
University of Arizona
2026-10-15 PHASE2
NCT07279610 ACTIVE_NOT_RECRUITING
Thrombotic Microangiopathy
The First Affiliated Hospital of Soochow University
2024-05-01 PHASE2; PHASE3
NCT07634991 RECRUITING
Diabetic Retinopathy (DR)
Ain Shams University
2026-01-10 PHASE4
NCT03652753 RECRUITING
Pilon Fracture
University of Missouri-Columbia
2019-01-01 PHASE4
NCT05557448 RECRUITING
Hepatitis
Sinew Pharma Inc.
2023-05-01 PHASE2
NCT04520139 RECRUITING
Ovarian Cancer; Cognitive Impairment
University of California, Irvine
2026-05-21 PHASE1; PHASE2
NCT07245095 RECRUITING
Esophagogastroduodenoscopy; Simethicone; N-Acetylcysteine; Premedication; Visualization; Esophagogastroduodensocopy (EGD) Procedure; Placebo - Control; Gastritis Associated With Helicobacter Pylori; Tumor Gastric; Lesions in the Esophagus, Stomach, Duodenum or Rectum
Hospital General de Mexicali
2025-09-12 PHASE2
NCT06377410 RECRUITING
Chronic Obstructive Pulmonary Disease
National University of Malaysia
2024-05-01
NCT06039566 RECRUITING
Hysterectomy
Medical University of South Carolina
2023-11-30 PHASE3
NCT07414212 RECRUITING
Amyotrophic Lateral Sclerosis
Biogipuzkoa Health Research Institute
2025-11-25 PHASE1; PHASE2
NCT05142735 RECRUITING
Prodromal Schizophrenia
Centre for Addiction and Mental Health
2023-01-13
NCT05509153 RECRUITING
Huntington Disease
Western Sydney Local Health District
2024-06-01 PHASE2
NCT05081479 ACTIVE_NOT_RECRUITING
Lymphoma
Memorial Sloan Kettering Cancer Center
2021-12-08 PHASE1
NCT07765823 RECRUITING
Acute Liver Failure
King Edward Medical University
2026-07-16
NCT06727422 RECRUITING
IBS (Irritable Bowel Syndrome); IBS-D (Diarrhea-predominant)
Mark Pimentel, MD
2026-02-04 PHASE2
NCT05994534 ACTIVE_NOT_RECRUITING
Cystinosis
Nacuity Pharmaceuticals, Inc.
2023-10-29 PHASE1; PHASE2
NCT06956482 RECRUITING
Alcoholic Hepatitis
University Hospital, Lille
2026-05-22 PHASE3
NCT02719392 WITHDRAWN
Bipolar Disorder; Bipolar Depression
Massachusetts General Hospital
2017-08-09 PHASE4
NCT07380347 NOT_YET_RECRUITING
Neonatal Sepsis
Ain Shams University
2026-02 PHASE3
NCT05294744 RECRUITING
Alcoholic Hepatitis
Bioaraba Health Research Institute
2022-10-07
NCT07567274 ENROLLING_BY_INVITATION
Tinnitus
Leading Edge Clinic
2026-05-15 PHASE2
NCT07196852 RECRUITING
Overweight (BMI > 25); Obesity
University of Thessaly
2025-09-22
NCT07301294 NOT_YET_RECRUITING
Double J Stent
Menoufia University
2026-01-01 PHASE4
NCT07262554 ACTIVE_NOT_RECRUITING
Apical Periodontitis
Alexandria University
2025-11-15 PHASE2
NCT06639178 RECRUITING
Breast Cancer
Centro di Riferimento Oncologico - Aviano
2024-08-01
NCT06311045 ACTIVE_NOT_RECRUITING
Obstructive Sleep Apnea
NYU Langone Health
2024-05-07
NCT04740580 RECRUITING
Alzheimer Disease
Baylor College of Medicine
2022-02-15 EARLY_PHASE1
NCT04987775 RECRUITING
Gulf War Syndrome
Nova Southeastern University
2023-11-30 EARLY_PHASE1
NCT07360379 NOT_YET_RECRUITING
Laparoscopic Appendectomy; Pain Management; Anti Oxidative Stress
Ain Shams University
2025-12-28
NCT05610072 COMPLETED
Cocaine Use Disorder; Opioid Use Disorder; Stimulant Use Disorder
William Stoops
2022-12-15 EARLY_PHASE1
NCT04300920 COMPLETED
Idiopathic Pulmonary Fibrosis
Fernando J Martinez
2020-12-17 PHASE3
NCT05241262 RECRUITING
Mitochondrial Disease
Michio Hirano, MD
2023-07-06 PHASE1
NCT07293884 NOT_YET_RECRUITING
Broncheictasis
Assiut University
2025-12
NCT06836128 RECRUITING
Polycystic Ovary Syndrome
Cairo University
2025-03-01 PHASE3
NCT06650384 COMPLETED
Nephrotoxicity
Ain Shams University
2024-11-01 PHASE2; PHASE3
NCT07391163 COMPLETED
Colorectal Cancer
Tanta University
2024-01-01
NCT05686356 ACTIVE_NOT_RECRUITING
Tuberculosis
The Aurum Institute NPC
2023-07-28 PHASE2; PHASE3
NCT02583672 COMPLETED
Gaucher Disease Type 1
University of Minnesota
2015-09 PHASE2
NCT07157722 NOT_YET_RECRUITING
Beta Thalassemia
Tanta University
2025-08-30 PHASE3
NCT07323719 COMPLETED
Atopic Dermatitis (AD)
Cairo University
2024-05-30
NCT06165068 RECRUITING
Dry Age-related Macular Degeneration
Navamindradhiraj University
2023-12 PHASE3
NCT07058090 NOT_YET_RECRUITING
Drug Induced Liver Injury; Tuberculosis (TB)
Liaquat National Hospital & Medical College
2025-07 PHASE1
NCT05408247 RECRUITING
Alcohol Use Disorder (AUD)
University of Sydney
2023-02-16 PHASE4
NCT07229456 ACTIVE_NOT_RECRUITING
Corrosive Injury
Ain Shams University
2024-10-01 PHASE3
NCT05517668 TERMINATED
Acetaminophen; Drug Overdose; Acetaminophen Overdose; Acetaminophen Poisoning; Drug-induced Liver Injury; Liver Failure; Liver Toxicity
Richard Dart, MD, PhD
2022-09-12 PHASE2
NCT03900988 UNKNOWN
Influenza
Chinese University of Hong Kong
2023-05-08 PHASE3
NCT05706402 UNKNOWN
Chronic Obstructive Pulmonary Disease
Queen Mary Hospital, Hong Kong
2023-09-18 PHASE3
NCT06384833 UNKNOWN
Rotator Cuff Tears
Mahidol University
2024-05-01 PHASE4
NCT06850831 COMPLETED
STEMI - ST Elevation Myocardial Infarction (MI); Primary PCI - STEMI
dr. Ahmad Yasa, Sp.JP, Subsp.K.I.(K), M.Kes, FIHA, FasCC, FA
2025-04-01 PHASE2
NCT05371288 WITHDRAWN
COVID-19
University of California, Irvine
2025-06 EARLY_PHASE1
NCT05907486 UNKNOWN
Thrombotic Disorder
The First Affiliated Hospital of Soochow University
2023-08-01 PHASE3
NCT06872372 ACTIVE_NOT_RECRUITING
Acute Liver Failure; Drug-Induced Liver Injury
Lahore General Hospital
2025-01-15
NCT04945096 UNKNOWN
Engraft Failure; Relapse; GVHD
The First Affiliated Hospital of Soochow University
2021-07-01 PHASE3
NCT06367413 RECRUITING
Aseptic Muscle Injury
University of Thessaly
2024-04-08
NCT04627922 COMPLETED
Cannabis Use; Tobacco Use Disorder; Drug Use Disorder
Ellen Herbst
2021-08-25 PHASE4
NCT05944458 COMPLETED
Linezolid; Antioxidant; Thrombocytopenia; Critical Illness; ICU
Helwan University
2023-08-01 PHASE4
NCT03493178 ACTIVE_NOT_RECRUITING
Mild Cognitive Impairment
Baylor College of Medicine
2018-04-19 EARLY_PHASE1
NCT06252441 COMPLETED
Post ERCP Pancreatitis
Tanta University
2024-03-16 PHASE1; PHASE2
NCT05070650 WITHDRAWN
Common Cold
Sandoz
2024-09-20 PHASE3
NCT05798481 COMPLETED
Hypertension; Cardiovascular Diseases
University of Alabama at Birmingham
2024-03-27 EARLY_PHASE1
NCT04459052 ACTIVE_NOT_RECRUITING
Parkinson Disease; Idiopathic Parkinson Disease
Thomas Jefferson University
2020-04-30 PHASE2
NCT06377631 COMPLETED
Visceral Obesity; Non-alcoholic Fatty Liver; Postmenopausal
Fundació Eurecat
2024-06-07
NCT05604586 COMPLETED
Skeletal Muscle Performance; Gene Polymorphisms
Poznan University of Life Sciences
2022-05-01
NCT07082621 COMPLETED
Oral Mucositis
Hams Hamed Abdelrahman
2024-01-15
NCT07325383 ACTIVE_NOT_RECRUITING
Oral Mucositis; Hematopoietic Stem Cell Transplantation (HSCT)
Tehran University of Medical Sciences
2024-08-18 PHASE3
NCT06354712 RECRUITING
Oral Mucositis (Ulcerative) Due to Radiation
Mansoura University
2024-04-04 PHASE2
NCT05309070 COMPLETED
Burning Mouth Syndrome
University of Zagreb
2022-05-01
NCT06297369 UNKNOWN
Cisplatin Adverse Reaction; Cisplatin Nephrotoxicity; Cisplatin Induced Peripheral Neuropathy; Cancer Patients; Cisplatin Ototoxicity
Ain Shams University
2024-02-01 PHASE2
NCT06236165 COMPLETED
Hepatic and Post Hepatic Jaundice
Tanta University
2024-02-14 PHASE2
NCT04964843 WITHDRAWN
Alcohol Use Disorder
Uniformed Services University of the Health Sciences
2023-04 PHASE2
NCT05074121 UNKNOWN
Covid19; COVID-19 Pneumonia; COVID-19 Respiratory Infection; COVID-19 Lower Respiratory Infection; SARS-CoV2 Infection; SARS-CoV-2 Acute Respiratory Disease; SARS-Associated Coronavirus as Cause of Disease Classified Elsewhere; Oxidative Stress
Cambridge Health Alliance
2024-03-31 PHASE2
NCT04793646 COMPLETED
Sjögren Syndrome; Sicca Syndrome
University of Sao Paulo General Hospital
2021-04-30
NCT03423667 TERMINATED
Cocaine Addiction
Salvatore Campanella
2019-03-01 PHASE2
NCT06834711 COMPLETED
Chronic Apical Periodontitis
Cukurova University
2024-02-15
NCT03911414 COMPLETED
Mood Disturbance; Mood Disorders; Natural Supplements; Alternative Treatment
Massachusetts General Hospital
2019-06-18 PHASE4
NCT04154982 COMPLETED
Cardiac Arrhythmia
Centro Cardiologico Monzino
2020-09-02 PHASE2
NCT04520139 Not yet recruiting
Ovarian Cancer|Cognitive Impairment
University of California Irvine|Jarrow Formulas Inc
2024-12 Phase 1|Phase 2
NCT06486805 COMPLETED
Oxidative Stress; Liver Dysfunction
Kasr El Aini Hospital
2024-06-30 PHASE4
NCT06956157 ACTIVE_NOT_RECRUITING
Obsessive Compulsive Disorder (OCD)
Guangdong Provincial People's Hospital
2022-06-22 PHASE4
NCT07097727 COMPLETED
Ventilator Associated Pneumonia ( VAP); Mechanical Ventilation
Tanta University
2023-10-30 PHASE1
NCT06482034 COMPLETED
Radiation-Induced Mucositis
Mansoura University
2023-06-28 PHASE2
NCT06484530 UNKNOWN
Tuberculosis (TB); Isoniazid Toxicity; Rifampicin Toxicity; Pyrazinamide Adverse Reaction; Ethambutol Toxicity; NAT2 Slow Acetylator Status; NAT2 Rapid Acetylator Status; NAT2 Polymorphism; N-Acetylcysteine
Mahidol University
2024-03-12 PHASE4
NCT04918719 COMPLETED
Acute Ischemic Stroke
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
2023-11-02 PHASE2
NCT06115408 COMPLETED
Uterine Leiomyoma
Ain Shams University
2023-09-01 PHASE2; PHASE3
NCT06039280 UNKNOWN
Hepatocellular Carcinoma
Institute of Liver and Biliary Sciences, India
2023-09-15
NCT04481048 COMPLETED
Neurofibromatosis 1
Children's Hospital Medical Center, Cincinnati
2021-02-23 PHASE2
NCT06105060 COMPLETED
Non-alcoholic Steatohepatitis
Beni-Suef University
2023-12-17 EARLY_PHASE1
NCT06122311 COMPLETED
Drug-Induced Nephropathy
Helwan University
2023-08-25
NCT05485558 COMPLETED
Drug Resistant Epilepsy
Tanta University
2022-09-15 PHASE2
NCT06112834 Not yet recruiting
Botulism
California Department of Public Health
2024-06 Phase 2
NCT05589584 COMPLETED
Simple Steatosis Non Fatty Liver
Ain Shams University
2022-11-01 PHASE3
NCT03757585 COMPLETED
Non-verbal Learning Disorder; Autism Spectrum Disorder; Autism
Massachusetts General Hospital
2019-05-20 PHASE4
NCT04291209 UNKNOWN
Ototoxic Hearing Loss
Sunnybrook Health Sciences Centre
2020-02-26 PHASE1; PHASE2
NCT06260566 Not yet recruiting
Biliary Atresia
Sanjiv Harpavat|Baylor College of Medicine
2024-05 Phase 1
NCT06377410 Not yet recruiting
Chronic Obstructive Pulmonary Disease
National University of Malaysia
2024-05-01 Not Applicable
NCT06223568 Not yet recruiting
Squamous Cell Carcinoma of the Head and Neck|Oropharynx|Human Papillomavirus Viruses|Drug Therapy|Cancer Vaccine
National Cancer Institute (NCI)|National Institutes of Health Clinical Center (CC)
2024-05-15 Phase 2
NCT05370729 UNKNOWN
Myocardial Injury
Assiut University
2022-05
NCT05804123 COMPLETED
Upper Respiratory Tract Infections
Anabio R&D
2021-10-28
NCT06202911 UNKNOWN
Preterm Neonates and Feeding Intolerance; Necrotizing Enterocolitis; Oral N-acetyl Cysteine
Ain Shams University
2023-01-01 PHASE4
NCT06139952 COMPLETED
Coronary Artery Disease; Nephropathy; Toxic, Drugs
Ain Shams University
2023-12-01 PHASE4
NCT04632069 COMPLETED
Infant of Diabetic Mother; Oxidative Stress; Vagus Nerve Stimulation; Feeding Disorders
Medical University of South Carolina
2021-08-12 EARLY_PHASE1
NCT03707951 COMPLETED
Alcohol Use Disorder
Medical University of South Carolina
2019-02-27 PHASE2
NCT06019520 UNKNOWN
Drug Toxicity
Foundation University Islamabad
2023-08-09
NCT03146130 TERMINATED
Impulse Control Disorder; Parkinson
Centre Hospitalier Universitaire, Amiens
2019-01-23 PHASE3
NCT05666089 UNKNOWN
Intracanal Medication; N-acetylcystine; Calcium Hydroxide; Mediators
Cairo University
2023-02-01 EARLY_PHASE1
NCT03055377 COMPLETED
Cannabis Use Disorder
Medical University of South Carolina
2017-08-03 PHASE2; PHASE3
NCT05287724 COMPLETED
Pruritus; Skin Disorder
Wright State University
2022-06-19 EARLY_PHASE1
NCT03956888 COMPLETED
Chronic Obstructive Pulmonary Disease
Siriraj Hospital
2019-05-01 PHASE3
NCT05807204 COMPLETED
Visceral Obesity; Non-Alcoholic Fatty Liver Disease
Fundació Eurecat
2023-05-01
NCT03720483 WITHDRAWN
Idiopathic Pulmonary Fibrosis (IPF)
University of Colorado, Denver
2022-01 PHASE1; PHASE2
NCT05539053 COMPLETED
Chemotherapy-induced Peripheral Neuropathy
Department of Medical Services Ministry of Public Health of Thailand
2022-11-01
NCT05985759 UNKNOWN
Evaluation of Post Endodontic Pain
Bapuji Dental College & Hospital Davengere Karnataka
2023-08-01 PHASE4
NCT03976973 UNKNOWN
Pseudomyxoma Peritonei; Peritoneal Cancer; Mucinous Adenocarcinoma; Mucinous Tumor
Mucpharm Pty Ltd
2022-05 PHASE2
NCT05906498 UNKNOWN
Psoriasis Vulgaris
Badr University
2022-12-01 PHASE3
NCT00585559 TERMINATED
Aneurysmal Subarachnoid Hemorrhage; Cerebral Vasospasm
Vanderbilt University Medical Center
2007-04 PHASE3
NCT05903014 COMPLETED
Nicotine Dependence; Nicotine Addiction
Indonesia University
2023-01-01 PHASE4
NCT03306979 COMPLETED
Vascular Cognitive Impairment no Dementia
Sunnybrook Health Sciences Centre
2018-04-30 PHASE2
NCT05460858 UNKNOWN
Female Infertility; Endometrioma; Stress Oxidative
Royan Institute
2021-04-13 PHASE3
NCT02972398 UNKNOWN
Major Depressive Disorders
Tianjin Anding Hospital
2015-09
NCT07080190 COMPLETED
Urine Alkalinization; N-Acetylcysteine; Hair Dye; Paraphenylene Diamine; Intoxication
South Valley University
2022-07-01
NCT05801055 UNKNOWN
Gastric Disease
Sanjay Gandhi Postgraduate Institute of Medical Sciences
2023-04-01 PHASE3
NCT03154580 COMPLETED
Marijuana Abuse
Wayne State University
2017-05-01 PHASE1
NCT05340504 COMPLETED
Bipolar Disorder; Bipolar I Disorder; Bipolar II Disorder
Medical University of South Carolina
2022-05-13 PHASE2
NCT04081012 UNKNOWN
Chronic Thromboembolic Pulmonary Hypertension
Instituto Nacional de Cardiologia Ignacio Chavez
2019-05-21
NCT04226456 TERMINATED
Ototoxic Hearing Loss; Ototoxic Hearing Loss, Bilateral; Ototoxicity; Tinnitus
Centre Hospitalier Universitaire Saint Pierre
2021-07-10 PHASE4
NCT05927259 COMPLETED
Acute Organophosphorus Poisoned Patients
Ain Shams University
2022-01-01 EARLY_PHASE1
NCT04920448 TERMINATED
Stroke, Ischemic
University Hospital, Caen
2021-06-16 PHASE2
NCT04703036 TERMINATED
Covid19
Baylor College of Medicine
2021-01-11 EARLY_PHASE1
NCT04712435 UNKNOWN
Sinusoidal Obstruction Syndrome (SOS); Hematopoietic Stem Cell Transplant (HSCT)
Instituto Brasileiro de Controle do Cancer
2021-04 PHASE2
NCT05738681 UNKNOWN
Tuberculosis; Drug Induced Liver Injury; Hepatitis
Mahidol University
2022-09-09 PHASE2; PHASE3
NCT04155632 COMPLETED
Cocaine-Related Disorders
Medical University of South Carolina
2020-12-18 PHASE2
NCT07470242 COMPLETED
Chronic Rhinosinusitis
Pusan National University Hospital
2021-10-13
NCT05089981 UNKNOWN
Acute on Chronic Liver Failure(ACLF)
Aga Khan University
2021-11-01
NCT02505477 COMPLETED
Schizophrenia; Cognitive Deficits; Schizophrenia; Negative Type
University of California, Los Angeles
2017-02-06 PHASE4
NCT05555511 UNKNOWN
Kidney Injury, Acute
Ain Shams University
2022-08-26
NCT05736887 UNKNOWN
COVID-19
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
2022-05-24 PHASE2
NCT07340944 COMPLETED
Chronic Apical Periodontitis
Ataturk University
2022-09-10
NCT07749287 COMPLETED
Ischemic Cerebral Infarction
Helwan University
2021-06-01 PHASE3
NCT04756622 UNKNOWN
Mucositis; Transplant-Related Disorder
moshe yeshurun
2021-04-01 PHASE3
NCT03220776 COMPLETED
Alcohol Use Disorder; Bipolar Disorder
Medical University of South Carolina
2017-08-07 PHASE2
NCT04766450 UNKNOWN
Diabetic Neuropathies
Ain Shams University
2021-12-01 PHASE4
NCT03499249 COMPLETED
Biliary Atresia
Baylor College of Medicine
2018-05-18 PHASE2
NCT05258682 UNKNOWN
COVID-19 Pneumonia; COVID-19; Ventilator Associated Pneumonia; COVID-19 Acute Respiratory Distress Syndrome
Mucpharm Pty Ltd
2022-05-01 PHASE1; PHASE2
NCT04594733 COMPLETED
Fibromyalgia
Medical University of South Carolina
2021-12-06 PHASE1; PHASE2
NCT05951712 COMPLETED
Mucosal Erosion
Asian Institute of Gastroenterology, India
2022-06-16
NCT05220605 COMPLETED
COVID-19 Pneumonia; Bromelains Adverse Reaction; Acetylcysteine Adverse Reaction; Mucus; Plug; COVID-19 Acute Respiratory Distress Syndrome
Mucpharm Pty Ltd
2022-07-27 PHASE1
NCT02124941 COMPLETED
Cocaine Dependence; Healthy
Yale University
2014-02 PHASE1
NCT04458298 TERMINATED
COVID-19
Ashvattha Therapeutics, Inc.
2020-08-11 PHASE2
NCT02445651 COMPLETED
Parkinson Disease; Idiopathic Parkinson Disease
Thomas Jefferson University
2014-03
NCT04015557 SUSPENDED
CBS Deficiency
Hospital de Clinicas de Porto Alegre
2022-02-11 PHASE1; PHASE2
NCT07374991 COMPLETED
COVID-19-Associated Acute Respiratory Distress Syndrome (ARDS)
University of Gaziantep
2020-11-01
NCT04916080 COMPLETED
Chronic Kidney Diseases
Beni-Suef University
2021-11-01 PHASE2
NCT03557229 UNKNOWN
Oxidative Stress; Septic Shock
American British Cowdray Medical Center
2018-07-23 PHASE3
NCT04562597 COMPLETED
Surgery
Medical University of South Carolina
2021-01-20 PHASE1; PHASE2
NCT04982146 UNKNOWN
Pseudomyxoma Peritonei
Maimónides Biomedical Research Institute of Córdoba
2021-09-13 PHASE1
NCT04005053 COMPLETED
Self-Harm; Depression; Suicide
University of Minnesota
2019-08-01 PHASE2
NCT03711838 COMPLETED
Satellite Cells; Redox Status; Exercise-induced Muscle Trauma; Aseptic Inflammation
University of Thessaly
2019-07-22
NCT04928495 UNKNOWN
COVID-19
Universidade Federal do Ceara
2021-07-15 PHASE3
NCT03069300 UNKNOWN
Alcoholic Hepatitis; Infection
Imperial College London
2015-10-01 PHASE3
NCT03238300 COMPLETED
Alcohol Drinking; Control
Medical University of South Carolina
2017-10-16 PHASE2
NCT04864496 UNKNOWN
Retinitis Pigmentosa
Shahid Beheshti University of Medical Sciences
2021-04-17 PHASE2
NCT03221231 UNKNOWN
Cannabis Use Disorder; Cannabis Dependence
Universitair Ziekenhuis Brussel
2016-05-15 PHASE4
NCT04904952 UNKNOWN
OCD
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
2020-03-13
NCT03702738 COMPLETED
Tuberculosis, Pulmonary
The Aurum Institute NPC
2019-03-01 PHASE2
NCT07093944 COMPLETED
Parkinson's Disease (PD)
Kurdistan University of Medical Sciences
2018-04-09 PHASE2
NCT03596125 TERMINATED
Preterm Delivery
Nantes University Hospital
2018-11-05 PHASE2; PHASE3
NCT03252925 COMPLETED
Thrombotic Microangiopathies; Hematologic Diseases
The First Affiliated Hospital of Soochow University
2017-11-01 PHASE3
NCT04509258 UNKNOWN
the Study Focus to Improve the Standard of Care Used for Aluminuim Phosphide Poisoning and to Save Patients With the Minimal Organ Damage
Cairo University
2020-10 PHASE4
NCT02966873 COMPLETED
Post Traumatic Stress Disorder (PTSD); Addiction; Alcohol Abuse
Medical University of South Carolina
2016-10-01 PHASE2
NCT04792021 COMPLETED
Corona Virus Disease 19 (Covid19); Corona Virus Infection; Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV2)
Ain Shams University
2021-03-09 PHASE3
NCT05064189 COMPLETED
Eye Diseases
Vienna Institute for Research in Ocular Surgery
2021-04-14
NCT05264584 COMPLETED
Chronic Kidney Disease stage3; Contrast-induced Nephropathy
Ain Shams University
2020-12-01
NCT03253328 COMPLETED
Diabetes Mellitus; Critical Limb Ischemia; Lower Limb Amputation Knee; Peripheral Arterial Disease
Washington University School of Medicine
2017-03-01 EARLY_PHASE1
NCT05049642 TERMINATED
Eye Diseases
Vienna Institute for Research in Ocular Surgery
2021-05-12
NCT04557215 COMPLETED
Irritable Bowel Syndrome With Diarrhea
Cedars-Sinai Medical Center
2020-11-13 PHASE1; PHASE2
NCT05049629 TERMINATED
Eye Diseases
Vienna Institute for Research in Ocular Surgery
2021-05-12
NCT04455243 UNKNOWN
COVID-19
Dr. Tariq Alhawassi
2020-08-01 PHASE3
NCT05053789 TERMINATED
Eye Diseases
Vienna Institute for Research in Ocular Surgery
2021-05-12
NCT05658549 COMPLETED
COVID-19
Universitas Sebelas Maret
2021-05-01 PHASE1; PHASE2
NCT04755972 COMPLETED
Corona Virus Infection; Pneumonia, Ventilator-Associated
Clinical Hospital Center, Split
2020-10-01
NCT04545008 TERMINATED
Covid19
Prisma Health-Upstate
2020-10-20 PHASE1
NCT04419025 COMPLETED
COVID; Sars-CoV2; SARS-Associated Coronavirus as Cause of Disease Classified Elsewhere; Oxidative Stress
Cambridge Health Alliance
2020-09-23 PHASE2
NCT04764643 COMPLETED
Esophageal Squamous Cell Carcinoma
Xijing Hospital of Digestive Diseases
2020-02-01
NCT03730064 COMPLETED
Bipolar Disorder; Depression
Martin Lan
2018-11-01 EARLY_PHASE1
NCT05840640 COMPLETED
Alcoholic Hepatitis
Post Graduate Institute of Medical Education and Research, Chandigarh
2017-10-01 PHASE4
NCT03346681 WITHDRAWN
Acute Respiratory Distress Syndrome
Prisma Health-Midlands
2018-02-01 EARLY_PHASE1
NCT03843541 COMPLETED
Respiratory Tract Diseases; Abnormal Mucus Secretions
Zambon SpA
2019-06-25 PHASE3
NCT03149107 TERMINATED
Prodromal Schizophrenia
University Hospital, Bonn
2016-09-01 PHASE3
NCT03902327 UNKNOWN
Insulin Resistance; Obesity; Carbohydrate Metabolism Disorder
Poznan University of Life Sciences
2020-01-17
NCT04368598 UNKNOWN
Immune Thrombocytopenia
Peking University People's Hospital
2019-04-01 PHASE2
NCT03510741 COMPLETED
Schizophrenia; Schizophreniform Disorders; Schizoaffective Disorder
Pakistan Institute of Living and Learning
2019-01-01 PHASE2
NCT04900129 COMPLETED
Covid19
Sher-E-Bangla Medical College
2020-12-01 PHASE1
NCT05611086 TERMINATED
Lymphoblastic Leukemia, Acute, Childhood
Teny Tjitra Sari
2019-08-29 PHASE4
NCT04570254 COMPLETED
Pneumonia, Viral; Covid19; ARDS; Oxidative Stress
Unidad Temporal COVID-19 en Centro Citibanamex
2020-08-19
NCT03322488 UNKNOWN
Perianal Fistula; Crohn Disease
University of Zurich
2017-06-20
NCT02788292 WITHDRAWN
Adipose Tissue Atrophy; Deformity of Reconstructed Breast; Graft Loss
Nova Scotia Health Authority
2016-08-15 PHASE4
NCT04023266 COMPLETED
STEMI
University of Alberta
2019-09-20 PHASE2
NCT04531163 UNKNOWN
Diabetic Kidney Disease; Diabetes Mellitus, Type 2; Diabetic Nephropathies
Al-Azhar University
2019-10-01 PHASE2; PHASE3
NCT03879759 UNKNOWN
Alcohol Dependence
South West Sydney Local Health District
2018-08-22 PHASE2
NCT04370288 UNKNOWN
Covid-19
Mashhad University of Medical Sciences
2020-04-19 PHASE1
NCT04209803 COMPLETED
Androgenetic Alopecia
Kafrelsheikh University
2018-12-01 PHASE4
NCT02094625 COMPLETED
Neuroectodermal Tumors, Primitive; Liver Neoplasms; Osteosarcoma; Other Childhood Cancers Using Cisplatin-based Regimens
Children's Hospital Los Angeles
2016-03 PHASE1
NCT02994875 COMPLETED
Cocaine Dependence
Yale University
2016-05 EARLY_PHASE1
NCT04405193 COMPLETED
Methamphetamine Dependence in Remission
Melva Louisa
2019-10-01 PHASE2; PHASE3
NCT03982537 WITHDRAWN
Head and Neck Cancer
Wake Forest University Health Sciences
2020-06-18 PHASE2
NCT04481035 COMPLETED
Neurofibromatosis 1
Children's Hospital Medical Center, Cincinnati
2019-01-15 PHASE2
NCT03364218 UNKNOWN
Bronchiolitis Acute
Carilion Clinic
2018-02-01 PHASE4
NCT04321980 COMPLETED
Healthy
Orpheris, Inc.
2020-03-19 PHASE1
NCT04291066 COMPLETED
Traumatic Brain Injury
HonorHealth Research Institute
2019-09-01 PHASE2
NCT03216954 COMPLETED
Alcohol Use Disorder
William Stoops
2017-09-15 EARLY_PHASE1
NCT03056014 TERMINATED
Ameliorating Oxidative Stress in Type 1 Diabetes
University of Maryland, Baltimore
2018-11-01 EARLY_PHASE1
NCT02723162 COMPLETED
Nicotine Dependence, Cigarettes
Medical University of South Carolina
2016-05-04 PHASE2
NCT03104725 TERMINATED
Parkinson Disease; Cerebrospinal Fluid
National Institute of Neurological Disorders and Stroke (NINDS)
2017-09-25 PHASE1
NCT03726450 UNKNOWN
Male Infertility
Andrology and Fertility Hospital of Hanoi
2018-11-01
NCT01800526 COMPLETED
Sickle Cell Disease; Sickle Cell Anemia
Bloodworks
2013-03 PHASE1; PHASE2
NCT03881163 COMPLETED
Respiratory Tract Disorders
Zambon SpA
2019-11-11 PHASE1
NCT03680911 TERMINATED
Anosmia; Head Trauma
University of Miami
2018-10-12 PHASE3
NCT03460808 UNKNOWN
Immune Thrombocytopenia
Peking University People's Hospital
2018-03-10 PHASE1; PHASE2
NCT03755700 UNKNOWN
Coronary Artery Disease; Coronary Artery Angiography; Coronary Catheterization; Contrast-induced Nephropathy; Stable Angina; Acute Coronary Syndrome
Rajaie Cardiovascular Medical and Research Center
2018-11-01 PHASE3
NCT03388853 COMPLETED
COPD
Neutec Ar-Ge San ve Tic A.Ş
2018-02-20 PHASE4
NCT05551624 COMPLETED
Primary Immune Thrombocytopenia
Hospital Civil de Guadalajara
2018-07-04 EARLY_PHASE1
NCT04260516 COMPLETED
Thalassemia Major
Beni-Suef University
2019-06-03 PHASE1
NCT00956748 WITHDRAWN
Otitis Media; Otorrhea
St. Paul's Hospital, Canada
2019-11-29 PHASE4
NCT03008889 COMPLETED
Autism Spectrum Disorder
Emory University
2018-07-05 PHASE2
NCT03556371 COMPLETED
Cocaine-Related Disorders
University of Concepcion, Chile
2018-04-09 PHASE2
NCT02911285 COMPLETED
Posttraumatic Stress Disorder (PTSD); Alcohol Use Disorder (AUD); Substance Use Disorder (SUD)
Medical University of South Carolina
2016-10 PHASE2
NCT01386645 COMPLETED
Impaired Glucose Tolerance; Oxidative Stress; Prediabetes; Impaired Fasting Glucose
Seattle Institute for Biomedical and Clinical Research
2011-07
NCT02737358 COMPLETED
Nicotine Dependence; Smoking
Medical University of South Carolina
2016-08-30 PHASE2
NCT02865629 UNKNOWN
Depression
University of Cincinnati
2016-08
NCT03120468 COMPLETED
Alcoholism
Nassima Ait-Daoud Tiouririne
2017-05-01 EARLY_PHASE1
NCT03281226 UNKNOWN
Tuberculosis, Pulmonary; HIV/AIDS
Fundação de Medicina Tropical Dr. Heitor Vieira Dourado
2016-12-07 PHASE2
NCT03492047 COMPLETED
Peripheral Neuropathy Due to Chemotherapy
Ain Shams University
2018-04-01 PHASE1; PHASE2
NCT03451435 TERMINATED
Endodontic Disease
University of California, Los Angeles
2018-06-15 EARLY_PHASE1
NCT03440268 UNKNOWN
Surgery--Complications; Cardiac Valve Disease; Acute Kidney Injury; Oxygen Radical Damage; Post-Op Complication
University of Sao Paulo General Hospital
2018-03-15 PHASE4
NCT01870193 COMPLETED
Aging
Rajagopal V Sekhar
2013-04-23 EARLY_PHASE1
NCT03063021 COMPLETED
Retinitis Pigmentosa
Johns Hopkins University
2017-02-15 PHASE1
NCT02182167 COMPLETED
Drug-Induced Liver Injury
University of Cape Town
2014-05 PHASE2; PHASE3
NCT03759158 COMPLETED
Liver Cirrhoses
Institute of Liver and Biliary Sciences, India
2018-12-01
NCT03708458 UNKNOWN
Post-ERCP Pancreatitis
Grigore T. Popa University of Medicine and Pharmacy
2017-04-01 PHASE4
NCT02348775 COMPLETED
HIV Infection; Erythrocyte Glutathione Deficiency
Baylor College of Medicine
2014-11 PHASE1
NCT02348762 COMPLETED
Aging; Erythrocyte Glutathione Deficiency; Muscle Weakness
Baylor College of Medicine
2014-11 PHASE1
NCT03354572 COMPLETED
Postoperative Pain
Radboud University Medical Center
2017-10-20 PHASE4
NCT02357290 COMPLETED
Bipolar Disorder
Massachusetts General Hospital
2014-01 PHASE4
NCT03177395 COMPLETED
Paracetamol Overdose
Egetis Therapeutics
2017-06-08 PHASE1
NCT03500627 COMPLETED
Healthy
Orpheris, Inc.
2018-03-30 PHASE1
NCT03581084 TERMINATED
Asthma
University of California, San Francisco
2018-07-06 PHASE4
NCT03018236 UNKNOWN
Cocaine Addiction; Alcohol Addiction
Hospital de Clinicas de Porto Alegre
2017-01 PHASE4
NCT03104959 TERMINATED
Prevention of Hangover Using N-Acety Cysteine
St. Luke's Hospital and Health Network, Pennsylvania
2016-01
NCT02804594 COMPLETED
Progressive Multiple Sclerosis; Fatigue
University of California, San Francisco
2016-10-01 PHASE2
NCT02269540 COMPLETED
Major Depressive Disorder
Centre for Addiction and Mental Health
2014-10 EARLY_PHASE1
NCT03164421 COMPLETED
PCOS
Zagazig University
2017-01 PHASE2
NCT02362425 COMPLETED
Neuromuscular Disease
National Institute of Nursing Research (NINR)
2015-02-12 PHASE1; PHASE2
NCT02791945 COMPLETED
Traumatic Brain Injury (TBI); Hazardous and Harmful Alcohol Use
University of California, San Francisco
2016-08 PHASE2
NCT02882477 UNKNOWN
Diabetes Mellitus; Iron Metabolism Disorders; Gastroduodenal Ulcer; Optic Atrophy; Sensorineural Hearing Loss; Platelet Dysfunction
Hadassah Medical Organization
2016-12 PHASE2; PHASE3
NCT02505087 TERMINATED
Selenoprotein N-related Myopathy
Assistance Publique - Hôpitaux de Paris
2015-09 PHASE2; PHASE3
NCT02117700 COMPLETED
Obesity; Nonalcoholic Fatty Liver Disease; Cardiovascular Disease
Nemours Children's Clinic
2015-04 PHASE1; PHASE2
NCT03197103 UNKNOWN
Breast; Deformity, Congenital; Graft Loss; Adipose Tissue Atrophy; Breast; Atrophy
Centre of Postgraduate Medical Education
2017-07-04 PHASE4
NCT01878344 ACTIVE_NOT_RECRUITING
Acute ST Segment Elevation Myocardial Infarction
Suleyman Demirel University
2013-01 PHASE3
NCT02088216 COMPLETED
Non-Cystic Fibrosis Bronchiectasis
Qilu Hospital of Shandong University
2014-04-01
NCT02481609 COMPLETED
Anosmia
University of Miami
2014-07 EARLY_PHASE1
NCT02206152 COMPLETED
Type 1 Diabetes; Hypoglycemia Unawareness
University of Minnesota
2015-02 PHASE1; PHASE2
NCT03014882 UNKNOWN
Endocrine Disease; Fertility Decreased Male; DNA Damage
Ain Shams University
2015-02 PHASE1; PHASE2
NCT02971306 UNKNOWN
Alcoholic Hepatitis
Post Graduate Institute of Medical Education and Research, Chandigarh
2014-07 PHASE4
NCT02476526 COMPLETED
Chronic Kidney Disease; Pulmonary Embolism; Renal Artery Stenosis; Pulmonary Cancer
VA Greater Los Angeles Healthcare System
2008-09 PHASE4
NCT01467466 COMPLETED
Acute Renal Failure; Kidney Disease; Coronary Artery Disease
VA Office of Research and Development
2013-10-07 PHASE3
NCT01878669 ACTIVE_NOT_RECRUITING
Coronary Artery Disease
Suleyman Demirel University
2013-01 PHASE3
NCT00637624 TERMINATED
Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell Lung; Mesothelioma
Rijnstate Hospital
2008-03
NCT01808521 COMPLETED
Purpura, Thrombotic Thrombocytopenic; TTP
Bloodworks
2013-05 EARLY_PHASE1
NCT03400709 COMPLETED
Cisplatin Adverse Reaction; Hearing Loss Ototoxic
Hospital San Juan de Dios, Santiago
2015-11
NCT03862586 COMPLETED
Female Infertility
Royan Institute
2015-02-01 PHASE3
NCT03241472 COMPLETED
Infertility
Assiut University
2016-02 PHASE3
NCT04643821 COMPLETED
HIE - Perinatal Hypoxic - Ischemic Encephalopathy
Medical University of South Carolina
2015-01-01 EARLY_PHASE1
NCT02794389 COMPLETED
Anorexia Nervosa; Compulsive Behavior
University of Oxford
2016-03
NCT02159196 COMPLETED
Respiratory Failure
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
2014-07
NCT02629536 UNKNOWN
Migraine, Headaches
University of Notre Dame Australia
2016-03 PHASE3
NCT02775734 COMPLETED
Clomiphene Citrate Resistant Polycystic Ovary Syndrome
Ain Shams University
2016-05 PHASE2; PHASE3
NCT01172275 COMPLETED
Obsessive-Compulsive Disorder
Yale University
2012-07 PHASE2
NCT01797575 COMPLETED
Bipolar Disorder
The University of Texas Health Science Center, Houston
2013-01 PHASE2
NCT02040818 WITHDRAWN
Hemodialysis Catheter-related Bacteremia
University of California, San Diego
2013-11 PHASE2; PHASE3
NCT01537926 COMPLETED
Hypertrophic Cardiomyopathy
The University of Texas Health Science Center, Houston
2012-01 PHASE1
NCT01664260 WITHDRAWN
Posttraumatic Stress Disorder
Ewha Womans University
2012-11-01 PHASE2
NCT02818270 COMPLETED
Chronic Obstructive Pulmonary Disease
Chang Gung University
2016-06
NCT02241876 UNKNOWN
Head and Neck Neoplasms
University of Campinas, Brazil
2014-10 PHASE4
NCT02294591 COMPLETED
Bipolar Disorder
Region Syddanmark
2014-11 PHASE2
NCT02686385 TERMINATED
Drug Induced Liver Injury
Institute of Liver and Biliary Sciences, India
2016-03-01
NCT01470027 COMPLETED
Parkinson Disease
Weill Medical College of Cornell University
2012-01 PHASE1; PHASE2
NCT02249546 UNKNOWN
Helicobacter Pylori Infection
National Taiwan University Hospital
2014-09 PHASE4
NCT04523675 COMPLETED
Skeletal Muscle Damage; Exercise-induced Aseptic Inflammation; Skeletal Muscle Performance; Antioxidant Status
University of Thessaly
2016-04
NCT03879356 COMPLETED
Detection of Different Prognostic Factors and Their Relation With the Outcome; Using New Protocol to Prove the Role of N-acetyl Cysteine and Adequate Supportive Measures in Aluminum Phosphide Poisoning
Assiut University
2016-01-01 PHASE4
NCT02569957 TERMINATED
Malignant Ovarian Endometrioid Tumor; Malignant Ovarian Serous Tumor; Recurrent Fallopian Tube Carcinoma; Recurrent Ovarian Carcinoma; Recurrent Primary Peritoneal Carcinoma
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
2015-10-02 PHASE2
NCT01849016 COMPLETED
Sickle Cell Disease
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
2013-04 PHASE3
NCT01866644 COMPLETED
Unspecified Complication of Liver Transplant
Instituto de Investigacion Sanitaria La Fe
2011-09 PHASE3
NCT02579772 COMPLETED
Pulmonary Disease, Chronic Obstructive
Queen's University
2015-07 PHASE4
NCT02420418 UNKNOWN
Bipolar Disorder
Universidade Estadual de Londrina
2015-07
NCT02688361 COMPLETED
Infections, Respiratory Tract
GlaxoSmithKline
2016-02-22 PHASE1
NCT00915200 COMPLETED
Diabetic Nephropathies; Proteinuria; Oxidative Stress
The University of Texas Health Science Center at San Antonio
2009-10 PHASE2
NCT02080182 COMPLETED
Pyelonephritis
Shahid Beheshti University of Medical Sciences
2014-01 PHASE2
NCT02141620 COMPLETED
Cocaine Abuse; Cocaine Dependence
University of Kentucky
2014-05 EARLY_PHASE1
NCT02123511 COMPLETED
Mucositis; Oral Complications; Recurrent Adenoid Cystic Carcinoma of the Oral Cavity; Recurrent Basal Cell Carcinoma of the Lip; Recurrent Lymphoepithelioma of the Nasopharynx; Recurrent Lymphoepithelioma of the Oropharynx; Recurrent Mucoepidermoid Carcinoma of the Oral Cavity; Recurrent Salivary Gland Cancer; Recurrent Squamous Cell Carcinoma of the Larynx; Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity; Recurrent Squamous Cell Carcinoma of the Nasopharynx; Recurrent Squamous Cell Carcinoma of the Oropharynx; Recurrent Verrucous Carcinoma of the Larynx; Recurrent Verrucous Carcinoma of the Oral Cavity; Stage I Adenoid Cystic Carcinoma of the Oral Cavity; Stage I Basal Cell Carcinoma of the Lip; Stage I Lymphoepithelioma of the Nasopharynx; Stage I Lymphoepithelioma of the Oropharynx; Stage I Mucoepidermoid Carcinoma of the Oral Cavity; Stage I Salivary Gland Cancer; Stage I Squamous Cell Carcinoma of the Larynx; Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage I Squamous Cell Carcinoma of the Nasopharynx; Stage I Squamous Cell Carcinoma of the Oropharynx; Stage I Verrucous Carcinoma of the Larynx; Stage I Verrucous Carcinoma of the Oral Cavity; Stage II Adenoid Cystic Carcinoma of the Oral Cavity; Stage II Basal Cell Carcinoma of the Lip; Stage II Lymphoepithelioma of the Nasopharynx; Stage II Lymphoepithelioma of the Oropharynx; Stage II Mucoepidermoid Carcinoma of the Oral Cavity; Stage II Salivary Gland Cancer; Stage II Squamous Cell Carcinoma of the Larynx; Stage II Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage II Squamous Cell Carcinoma of the Nasopharynx; Stage II Squamous Cell Carcinoma of the Oropharynx; Stage II Verrucous Carcinoma of the Larynx; Stage II Verrucous Carcinoma of the Oral Cavity; Stage III Adenoid Cystic Carcinoma of the Oral Cavity; Stage III Basal Cell Carcinoma of the Lip; Stage III Lymphoepithelioma of the Nasopharynx; Stage III Lymphoepithelioma of the Oropharynx; Stage III Mucoepidermoid Carcinoma of the Oral Cavity; Stage III Salivary Gland Cancer; Stage III Squamous Cell Carcinoma of the Larynx; Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage III Squamous Cell Carcinoma of the Nasopharynx; Stage III Squamous Cell Carcinoma of the Oropharynx; Stage III Verrucous Carcinoma of the Larynx; Stage III Verrucous Carcinoma of the Oral Cavity; Stage IV Lymphoepithelioma of the Nasopharynx; Stage IV Squamous Cell Carcinoma of the Nasopharynx; Stage IVA Adenoid Cystic Carcinoma of the Oral Cavity; Stage IVA Basal Cell Carcinoma of the Lip; Stage IVA Lymphoepithelioma of the Oropharynx; Stage IVA Mucoepidermoid Carcinoma of the Oral Cavity; Stage IVA Salivary Gland Cancer; Stage IVA Squamous Cell Carcinoma of the Larynx; Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage IVA Squamous Cell Carcinoma of the Oropharynx; Stage IVA Verrucous Carcinoma of the Larynx; Stage IVA Verrucous Carcinoma of the Oral Cavity; Stage IVB Adenoid Cystic Carcinoma of the Oral Cavity; Stage IVB Basal Cell Carcinoma of the Lip; Stage IVB Lymphoepithelioma of the Oropharynx; Stage IVB Mucoepidermoid Carcinoma of the Oral Cavity; Stage IVB Salivary Gland Cancer; Stage IVB Squamous Cell Carcinoma of the Larynx; Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage IVB Squamous Cell Carcinoma of the Oropharynx; Stage IVB Verrucous Carcinoma of the Larynx; Stage IVB Verrucous Carcinoma of the Oral Cavity; Stage IVC Adenoid Cystic Carcinoma of the Oral Cavity; Stage IVC Basal Cell Carcinoma of the Lip; Stage IVC Lymphoepithelioma of the Oropharynx; Stage IVC Mucoepidermoid Carcinoma of the Oral Cavity; Stage IVC Salivary Gland Cancer; Stage IVC Squamous Cell Carcinoma of the Larynx; Stage IVC Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage IVC Squamous Cell Carcinoma of the Oropharynx; Stage IVC Verrucous Carcinoma of the Larynx; Stage IVC Verrucous Carcinoma of the Oral Cavity; Tongue Cancer
Mayo Clinic
2014-04 PHASE2
NCT02822287 COMPLETED
Common Cold
GlaxoSmithKline
2016-02 PHASE3
NCT03121222 COMPLETED
Glutathione Metabolism Anemias
Aristotle University Of Thessaloniki
2015-11-01 PHASE2
NCT01612221 COMPLETED
Patients at Risk for Melanoma
University of Utah
2012-09 PHASE2
NCT02930031 COMPLETED
Skeletal Muscle Damage; Aseptic Inflammation; Skeletal Muscle Function
National and Kapodistrian University of Athens
2015-01
NCT01381354 COMPLETED
Multiple Sclerosis
University of Iowa
2010-10 PHASE1
NCT02357303 COMPLETED
Gastric Mucosal Lesion
Portuguese Oncology Institute, Coimbra
2015-04 PHASE4
NCT01739790 TERMINATED
COPD; Chronic Bronchitis
University of Minnesota
2013-01
NCT01339858 COMPLETED
Schizophrenia; Psychotic Disorder NOS; Schizoaffective Disorder; Schizophreniform
Indiana University
2011-05 PHASE4
NCT01037465 COMPLETED
Cardiovascular Disease
Boston University
2008-09
NCT02541422 COMPLETED
Hangover Symptoms, NAC
St. Luke's Hospital and Health Network, Pennsylvania
2015-08
NCT02493933 UNKNOWN
Infertility
Kasr El Aini Hospital
2015-07 PHASE1
NCT00896025 TERMINATED
Acute Liver Failure; Fulminant Hepatic Failure
University of Texas Southwestern Medical Center
2008-12 PHASE4
NCT02760901 COMPLETED
Cisplatin Nephrotoxicity
Ain Shams University
2013-11 PHASE2
NCT01214083 COMPLETED
Alcoholism
VA Office of Research and Development
2010-10-15 PHASE2
NCT02252341 UNKNOWN
Bipolar Disorder
Universidade Estadual de Maringá
2014-09 PHASE4
NCT02212678 COMPLETED
Parkinson Disease
University of Minnesota
2014-09 PHASE2
NCT01063348 COMPLETED
Pathologic Skin Picking; Neurotic Excoriation; Psychogenic Excoriation; Dermatillomania
University of Chicago
2012-09 PHASE2
NCT01675661 COMPLETED
Cannabis Dependence
Medical University of South Carolina
2014-01 PHASE3
NCT03679442 COMPLETED
Drug-Induced Acute Liver Injury
University of Aarhus
2014-09-08 PHASE1
NCT01993849 COMPLETED
Onychophagia
Kevin Gray, MD
2013-10 PHASE3
NCT01962961 COMPLETED
HIV; Endothelial Dysfunction; Oxidative Stress
Indiana University
2013-10 PHASE1; PHASE2
NCT01878695 COMPLETED
Stage 0/1 Breast Cancer; Post Biopsy; Pre-surgery
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
2012-07-26 PHASE1
NCT01111734 COMPLETED
Deliberate Self Harm
University of Minnesota
2011-03 PHASE1
NCT00870883 COMPLETED
Hypotension; Acute Renal Failure
Universidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da Saude
2009-03 PHASE2
NCT02015403 COMPLETED
Ischemic Hepatitis
Institute of Liver and Biliary Sciences, India
2013-12
NCT01384591 COMPLETED
Aging
The University of Texas Medical Branch, Galveston
2011-07 PHASE1; PHASE2
NCT02379637 COMPLETED
Common Cold Associated With Cough
Novartis
2015-01 PHASE2
NCT01265563 COMPLETED
Diabetic Nephropathy; Proteinuria; Oxidative Stress
VA Office of Research and Development
2011-01 PHASE2
NCT02483143 COMPLETED
Radiographic Contrast Agent Nephropathy; Pulmonary Embolism
Karadeniz Technical University
2014-02 PHASE4
NCT02707640 COMPLETED
Idiopathic Pulmonary Fibrosis
Hoffmann-La Roche
2013-08 PHASE2
NCT00558142 COMPLETED
Radiocontrast-induced Nephropathy
University of Edinburgh
2008-02 PHASE4
NCT02054949 WITHDRAWN
Autistic Disorder; Seizures; Irritability
Nationwide Children's Hospital
2013-04
NCT01138137 WITHDRAWN
Ovarian Carcinoma, Stage 3 or 4; Epithelial Ovarian Carcinoma; Primary Peritoneal Carcinoma
OHSU Knight Cancer Institute
2010-06 PHASE1
NCT01555970 COMPLETED
Obsessive-Compulsive Disorder
University of Sao Paulo
2012-03 PHASE2
NCT01210456 UNKNOWN
Chronic Kidney Disease
Tokushukai Medical Group
2009-10 PHASE3
NCT01587001 COMPLETED
Pulmonary Sarcoidosis
National Jewish Health
2011-11
NCT02335060 TERMINATED
Healthy
Yale University
2014-05-02 EARLY_PHASE1
NCT00575419 TERMINATED
Contrast Induced Nephropathy
Oregon Health and Science University
2007-11 PHASE1
NCT02499029 COMPLETED
PTSD; Addiction
Medical University of South Carolina
2013-02 PHASE2
NCT02265224 COMPLETED
no Condition
Zambon SpA
2014-09 PHASE1
NCT01394510 COMPLETED
Type 2 Diabetes; Oxidative Stress
Utzschneider, Kristina, M.D.
2011-06
NCT01891292 UNKNOWN
Microalbuminuria; Sickle Cell Nephropathy
The University of The West Indies
2013-07
NCT01354132 COMPLETED
Schizophrenic Psychoses
Beth Israel Deaconess Medical Center
2011-05 PHASE2
NCT00724594 COMPLETED
Chorioamnionitis; Brain Injury
Medical University of South Carolina
2008-08 PHASE1; PHASE2
NCT01907061 COMPLETED
Acute Renal Failure
Baylor Research Institute
2007-07
NCT02723669 COMPLETED
Healthy
Arbor Pharmaceuticals, Inc.
2014-04 PHASE1
NCT01885338 COMPLETED
Schizophrenia
VA Greater Los Angeles Healthcare System
2013-06 PHASE1
NCT02088502 UNKNOWN
Contrast-Induced Nephropathy
Isfahan University of Medical Sciences
2013-09 PHASE2; PHASE3
NCT02124525 UNKNOWN
Tobacco Smoking; Oxidative Stress; Inflammation
Universidade Estadual de Londrina
2013-02 PHASE3
NCT01586533 UNKNOWN
Ulcerative Colitis; Left-sided Ulcerative Colitis; Distal Ulcerative Colitis
Altheus Therapeutics, Inc.
2012-06 PHASE2
NCT01172288 COMPLETED
Tourettes Syndrome; Tic
Yale University
2010-07 PHASE2
NCT02206178 COMPLETED
Healthy
University Hospital, Clermont-Ferrand
2013-09 PHASE1
NCT00614757 SUSPENDED
Insulin Resistance; Metabolic Syndrome x
Midwest Biomedical Research
2005-05
NCT01322009 COMPLETED
Pediatric Traumatic Brain Injury
University of Pittsburgh
2011-03 PHASE1; PHASE2
NCT02239107 COMPLETED
Polycystic Ovary Syndrome
Assiut University
2012-01 PHASE4
NCT01495260 COMPLETED
Adrenomyeloneuropathy
Pujol, Aurora, M.D.
2011-09 PHASE2
NCT00028262 COMPLETED
Infantile Neronal Ceroid Lipofuscinosis
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
2001-02 PHASE4
NCT00650091 COMPLETED
Pulmonary Fibrosis
Duke University
2009-10 PHASE3
NCT01653171 COMPLETED
Stomach Neoplasms
Pontificia Universidad Catolica de Chile
2012-07 PHASE4
NCT01726465 TERMINATED
Ischemic Reperfusion Injury; Insufficiency; Hepatic, Postoperative; Liver Tumour
Istituto Clinico Humanitas
2012-11 PHASE2
NCT01187108 COMPLETED
Erythrocytosis; Mountain Sickness
University of Colorado, Denver
2013-06 PHASE1; PHASE2
NCT01251029 UNKNOWN
Chronic Kidney Diseases; General Anesthesia
Assaf-Harofeh Medical Center
2011-01 PHASE1
NCT01905696 TERMINATED
Focus is Determination of the Role of SNO-Hb in Forearm Blood Flow Regulation
Duke University
2013-03 EARLY_PHASE1
NCT01501110 COMPLETED
Acute Myocardial Infarction; Euthyroid Sick Syndrome; Ischemic Heart Disease
Federal University of Rio Grande do Sul
2011-11 PHASE4
NCT02761577 COMPLETED
Kidney Diseases; Contrast Media Reaction
Clinical Hospital Centre Zagreb
2012-06 PHASE4
NCT00497328 COMPLETED
Contrast Induced Nephropathy
National University Hospital, Singapore
2007-08 PHASE2; PHASE3
NCT01896492 COMPLETED
PCOS
Woman's Health University Hospital, Egypt
2011-01 PHASE4
NCT01841411 UNKNOWN
Bacterial Vaginosis
Minia University
2013-03 PHASE4
NCT01599884 UNKNOWN
Chronic Obstructive Pulmonary Disease; Chronic Bronchitis
Center for Veterans Research and Education
2012-06
NCT00525551 COMPLETED
Otosclerosis
Karolinska University Hospital
2007-09 PHASE4
NCT01160627 COMPLETED
Contrast Induced Nephropathy
Odense University Hospital
2010-04
NCT01753752 COMPLETED
Dry Eye Syndrome
Gerhard Garhofer
2012-09 PHASE2
NCT01424033 TERMINATED
Interstitial Lung Disease; Connective Tissue Disease
University of Michigan
2011-12 PHASE2; PHASE3
NCT01427517 COMPLETED
Parkinson's Disease; Gaucher's Disease
University of Minnesota
2011-07 PHASE1
NCT01050270 COMPLETED
Overdose
University of Edinburgh
2010-09 PHASE4
NCT00467831 TERMINATED
Hermansky-Pudlak Syndrome (HPS); Pulmonary Fibrosis; Oculocutaneous Albinism; Platelet Storage Pool Deficiency; Metabolic Disease
National Human Genome Research Institute (NHGRI)
2007-04 PHASE1; PHASE2
NCT01118663 TERMINATED
Acetaminophen Overdose
Cumberland Pharmaceuticals
2010-09 PHASE3
NCT00397735 COMPLETED
Labor, Premature; Preterm Premature Rupture of the Membranes; Infection; Inflammation; Chorioamnionitis
Ohio State University
2006-10-01 PHASE1; PHASE2
NCT00967005 COMPLETED
Gambling; Tobacco Use Disorder
University of Chicago
2009-09 PHASE2
NCT01704482 COMPLETED
Cardiac Surgery for Rheumatic Valvular Heart Disease; Renal Dysfunction
Assiut University
2011-02 PHASE2
NCT01550432 COMPLETED
Obesity; Hyperlipidemia; Insulin Resistance; Hypertension
Stanford University
2011-06
NCT02168387 COMPLETED
Atelectasis
Duke University
2010-12 PHASE4
NCT01403506 UNKNOWN
Disorder Related to Renal Transplantation
Shahid Beheshti University of Medical Sciences
2011-04 PHASE3
NCT01394419 COMPLETED
Postoperative Acute Kidney Injury After Off-pump Coronary Artery Bypass Graft
Yonsei University
2010-09 PHASE4
NCT00993265 COMPLETED
Trichotillomania; Hair Pulling
Yale University
2009-10 PHASE2
NCT01033149 TERMINATED
Bulimia Nervosa
Lindner Center of HOPE
2009-12 PHASE3
NCT01131572 TERMINATED
NAC
Lindner Center of HOPE
2010-02 PHASE2; PHASE3
NCT01136239 COMPLETED
COPD
Kwong Wah Hospital
2010-02 PHASE4
NCT01439828 TERMINATED
Cannabis Dependence; Cannabis Abuse
Assistance Publique - Hôpitaux de Paris
2012-02 PHASE2
NCT01614431 COMPLETED
Renal Disease; Cystinosis
University of Sao Paulo
2011-03 PHASE4
NCT01359722 UNKNOWN
Kidney Failure, Acute; Oxidative Stress Induction
Instituto do Coracao
2010-03
NCT01747616 COMPLETED
Dry Eye Syndrome
Medical University of Vienna
2011-07 PHASE1
NCT01232790 COMPLETED
Schizophrenia
Yale University
2010-02
NCT01699204 COMPLETED
Asthma
University of British Columbia
2007-09
NCT01778309 COMPLETED
Skeletal Muscle Damage; Skeletal Muscle Performance; Intgracellular Signaling in Skeletal Muscle; Inflammatory Status
Democritus University of Thrace
2010-01
NCT01355198 COMPLETED
HIV Infection; Erythrocyte Glutathione Deficiency
Baylor College of Medicine
2010-08 PHASE1
NCT00893724 UNKNOWN
Neovascular Age-related Macular Degeneration; Diabetic Macular Edema
Mid-Atlantic Retina Consultations, Inc.
2009-06
NCT01005810 COMPLETED
Cannabis Dependence
Medical University of South Carolina
2009-09 PHASE2
NCT01209455 COMPLETED
Poisoning
University of Edinburgh
2011-01-03
NCT01063205 COMPLETED
Methamphetamine Abuse; Methamphetamine Dependence; Substance Abuse
Baylor College of Medicine
2010-03 PHASE1
NCT01597765 COMPLETED
Thalassemia
Mahidol University
2009-06
NCT01278784 COMPLETED
Dry Eye Syndromes
Medical University of Vienna
2011-03 PHASE1
NCT01138956 UNKNOWN
Visceral Leishmaniasis; Immune Response; Treatment
Hospital Universitário Professor Edgard Santos
2010-04
NCT01251315 COMPLETED
Oxidative Stress
Charles Drew University of Medicine and Science
2010-12 PHASE1
NCT00539513 TERMINATED
Obsessive-Compulsive Disorder
Yale University
2006-06 PHASE2
NCT00809094 COMPLETED
Cystic Fibrosis
Stanford University
2008-11 PHASE2
NCT00611897 COMPLETED
Cognitive Dysfunction
Yale University
2006-01 PHASE1; PHASE2
NCT00969904 COMPLETED
COPD
University Hospital, Antwerp
2009-03 PHASE4
NCT00391911 COMPLETED
Rhabdomyolysis
Royal Alexandra Hospital
2006-11 PHASE2
NCT01111422 UNKNOWN
End-Stage Kidney Disease; Peritoneal Dialysis
Ewha Womans University
2010-03 PHASE4
NCT00998972 COMPLETED
Brain Death; Chronic Renal Insufficiency
Institut d'Anesthesiologie des Alpes Maritimes
2006-09 PHASE3
NCT00975689 COMPLETED
Niemann-Pick Disease, Type C
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
2009-08 PHASE1; PHASE2
NCT00539188 TERMINATED
Borderline Personality Disorder; Self-Injurious Behavior
Yale University
2007-09 PHASE2
NCT01082445 COMPLETED
Foot Ulcer, Diabetic
University of Turin, Italy
2009-08 PHASE3
NCT01188005 UNKNOWN
Obstructive Sleep Apnea Syndrome
University of Athens
2010-08
NCT01015209 COMPLETED
Dry Eye Syndromes
Medical University of Vienna
2010-09 PHASE1
NCT00627705 COMPLETED
Autistic Disorder
Stanford University
2008-02 PHASE2
NCT00996424 TERMINATED
Cystic Fibrosis
University Hospital, Ghent
2010-01 PHASE4
NCT01020708 COMPLETED
Ulcerative Colitis
Altheus Therapeutics, Inc.
2009-11 PHASE1
NCT00780962 COMPLETED
Radiocontrast Nephropathy
Beth Israel Deaconess Medical Center
2007-10-16 PHASE2
NCT00434005 COMPLETED
Healthy
University of Washington
2008-07
NCT00736866 COMPLETED
Acute Kidney Failure
Hospital do Coracao
2008-08 PHASE3
NCT01047956 UNKNOWN
Opioids Use
Taichung Veterans General Hospital
2009-06 PHASE4
NCT00676195 COMPLETED
Autistic Disorder
Stanford University
2008-06 PHASE2
NCT00939913 UNKNOWN
Nephropathy
Ochsner Health System
2007-01 PHASE4
NCT00218491 COMPLETED
Cocaine Dependence
Medical University of South Carolina
2005-11 PHASE2
NCT00579995 TERMINATED
Nephropathy
University of Nebraska
2005-05-01
NCT01131468 COMPLETED
Drug-induced Ototoxicity in Peritoneal Dialysis Patients
TC Erciyes University
2008-02 PHASE2
NCT01017796 UNKNOWN
Contrast Induced Nephropathy
University of Thessaly
2009-01 EARLY_PHASE1
NCT00866866 UNKNOWN
Chronic Sinonasal Symptoms
University of Calgary
2009-03 PHASE4
NCT00332605 COMPLETED
Methamphetamine Dependence
University of Chicago
2006-06 PHASE2
NCT00440869 COMPLETED
End-Stage Renal Disease; Dialysis; Hemodialysis
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
2007-03 PHASE1
NCT00248625 COMPLETED
Acute Liver Failure; Hepatic Encephalopathy
University of Pittsburgh
2000-01 PHASE3
NCT00568087 COMPLETED
Alcoholism
Minneapolis Veterans Affairs Medical Center
2007-12 PHASE1; PHASE2
NCT00863785 COMPLETED
Alcoholic Hepatitis
Centre Hospitalier Universitaire, Amiens
2004-04 PHASE3
NCT00655928 COMPLETED
Acute Lung Injury
Imperial College London
2007-08 PHASE2
NCT00716001 UNKNOWN
Chronic Renal Failure
Osaka General Medical Center
2008-07 PHASE4
NCT01008046 COMPLETED
Polycystic Ovary Syndrome
Mansoura University
2007-04
NCT01612013 COMPLETED
Acute Renal Failure
Federal University of São Paulo
2005-05
NCT00822263 COMPLETED
Mild Traumatic Brain Injury
Brooke Army Medical Center
2008-11
NCT00564642 COMPLETED
Hepatitis; Tuberculosis
National Research Institute of Tuberculosis and Lung Disease, Iran
2007-11
NCT00483314 COMPLETED
Homocystinuria
McGill University Health Centre/Research Institute of the McGill University Health Centre
2007-11 PHASE2
NCT00542750 COMPLETED
Cannabis Dependence
Medical University of South Carolina
2008-01 PHASE1; PHASE2
NCT00787813 COMPLETED
Cervical Cerclage
Assiut University
2008-06
NCT00506506 COMPLETED
Chronic Kidney Disease
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
2007-10 PHASE3
NCT00354770 COMPLETED
Trichotillomania
University of Chicago
2006-07 PHASE2
NCT00512265 COMPLETED
Pulmonary Morbidity
University Hospital, Basel, Switzerland
2006-01 PHASE4
NCT00374088 COMPLETED
Transposition of Great Vessels; Congenital Heart Disease
University of Michigan
2005-02 PHASE2
NCT00493610 SUSPENDED
Hepatitis C
US Department of Veterans Affairs
2006-11
NCT00994305 UNKNOWN
Renal Transplantation
University of Sao Paulo General Hospital
2005-04
NCT00267384 COMPLETED
Drug Induced Nephrotoxicity
Soroka University Medical Center
2006-03 PHASE2; PHASE3
NCT00498342 COMPLETED
Chronic Kidney Disease
University of Vermont
2007-06
NCT00353340 COMPLETED
Acute Renal Failure Contrast Nephropathy
Shaare Zedek Medical Center
2005-01
NCT00552786 COMPLETED
Hearing Loss
National Taiwan University Hospital
2007-11 PHASE2
NCT01223326 COMPLETED
Hepatectomy; Reperfusion Injury
Clinica Universidad de Navarra, Universidad de Navarra
2003-01 PHASE4
NCT00751257 COMPLETED
Nicotine Dependence
Medical University of South Carolina
2006-12 PHASE2
NCT00188773 COMPLETED
Insulin Resistance Syndrome X; Pancreatic Beta Cell Function
University Health Network, Toronto
2004-01 PHASE4
NCT00736541 COMPLETED
End Stage Liver Failure
Ibtesam Hilmi
2004-07
NCT00188630 COMPLETED
Heart Disease; Acute Renal Failure
University Health Network, Toronto
2003-07 PHASE3
NCT00004467 COMPLETED
Acute Liver Failure
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
1998-06 PHASE3
NCT00808795 COMPLETED
Radiocontrast-Induced Nephropathy; Chronic Kidney Disease; Diabetes Mellitus
Tehran University of Medical Sciences
2006-04 PHASE3
NCT00203099 COMPLETED
Relapse Remitting Multiple Sclerosis
Teva Branded Pharmaceutical Products R&D, Inc.
2004-12 PHASE2
NCT00122018 COMPLETED
Kidney Failure, Acute; Kidney Failure, Chronic; Cardiac Surgical Procedures
Linda F. Barr, M.D.
2002-05 PHASE2
NCT00238173 TERMINATED
Bone Marrow Suppression; Brain and Central Nervous System Tumors; Drug/Agent Toxicity by Tissue/Organ; Long-term Effects Secondary to Cancer Therapy in Children
OHSU Knight Cancer Institute
2004-12 PHASE1
NCT00962442 COMPLETED
Alcoholic Hepatitis
Erasme University Hospital
2000-09 PHASE3
NCT00830193 COMPLETED
Contrast Induced Nephropathy; Critically Ill
Unity Health Toronto
2002-08 PHASE2; PHASE3
NCT01506765 COMPLETED
Schizophrenia
Centre Hospitalier Universitaire Vaudois
2003-08 PHASE1
NCT00639496 COMPLETED
Pulmonary Fibrosis
Zambon SpA
2000-03 PHASE3
NCT00003346 COMPLETED
Melanoma (Skin)
Memorial Sloan Kettering Cancer Center
1997-11 PHASE2
NCT00421785 UNKNOWN
ESRD; Peritoneal Dialysis
Assaf-Harofeh Medical Center
2007-02
NCT01137591 WITHDRAWN
Liver Failure; Liver Failure, Acute; Drug Induced Liver Injury; Prevention & Control; Fever
Columbia University
2009-04
NCT00247507 UNKNOWN
Anemia; Atherosclerosis; End-Stage Renal Disease; Oxidative Stress; Pro-Inflammation
Far Eastern Memorial Hospital
2005-09 PHASE4
NCT00356954 COMPLETED
Kidney Failure
Seoul National University Hospital
2005-02 PHASE4
NCT00399256 TERMINATED
Chronic Kidney Failure
Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF)
2004-03
NCT01021163 COMPLETED
Coronary Artery Occlusion
Yonsei University
PHASE4
NCT00492518 COMPLETED
Contrast Induced Nephropathy; Kidney Diseases; Renal Failure; Adverse Effects
Technical University of Munich
2002-02 PHASE4
NCT00569465 TERMINATED
Type 2 Diabetes Mellitus; Hypertension
University of Turin, Italy
2005-01 PHASE4
NCT00532688 UNKNOWN
Heart Failure, Congestive; Kidney Failure, Chronic
Bayside Health
2007-09 PHASE2; PHASE3
NCT00196885 COMPLETED
Gastrointestinal Neoplasms; Bronchial Carcinoma; Hodgkin Disease; Non-Hodgkin Lymphoma; Weight Loss
German Cancer Research Center
2003-12 PHASE2
NCT00572663 COMPLETED
Chronic Kidney Disease; Proteinuria
Medical University of Gdansk
2005-01
NCT00237614 COMPLETED
Contrast-Induced Nephropathy; Acute Myocardial Infarction
University of Milan
2003-02 PHASE2; PHASE3
NCT00190034 SUSPENDED
Cardiovascular Disease; Renal Insufficiency, Acute; Cardiopulmonary Bypass
Far Eastern Memorial Hospital
2005-01 PHASE4
NCT00463671 COMPLETED
Diabetic Foot Ulcers
Assaf-Harofeh Medical Center
2003-12
NCT00187330 COMPLETED
Heart Disease; Renal Insufficiency
Sunnybrook Health Sciences Centre
2004-03 PHASE2
NCT00428883 UNKNOWN
Scleroderma, Diffuse
Università Politecnica delle Marche
2007-01 PHASE2; PHASE3
NCT00136825 COMPLETED
Cocaine-Related Disorders
National Institute on Drug Abuse (NIDA)
2003-03 PHASE1
NCT00851708 COMPLETED
Deceased Kidney Transplantation
University of Sao Paulo
NCT00332631 COMPLETED
Cardiac Surgery and Cardiopulmonary Bypass
Austin Health
2004-08 PHASE2
NCT00568113 COMPLETED
Preterm Labour
Assiut University
2007-07 PHASE4
NCT00592618 UNKNOWN
ESRD; Sleep Apnea
Assaf-Harofeh Medical Center
NCT00184977 COMPLETED
Pulmonary Disease, Chronic Obstructive; Lung Diseases, Obstructive; Bronchitis, Chronic
Radboud University Medical Center
1998-12 PHASE4
NCT00556465 COMPLETED
Diabetic Nephropathy; Chronic Kidney Disease; Diabetes Type 2
Shiraz University of Medical Sciences
2007-01 PHASE2; PHASE3
NCT00507052 UNKNOWN
Hemodialysis; Renal Failure
Assaf-Harofeh Medical Center

(data from https://clinicaltrials.gov, updated on 2025-08-22)

Check the N-Acetylcysteine (NAC chemical, N-Acetyl-L-Cysteine) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Compliance for Clinical Use

Mechanism and Biochemical Profile

Acetylcysteine acts as a direct reactive oxygen species inhibitor and quenches free radicals while suppressing IκB kinase activity to block downstream TNF-induced NF-κB signal transduction. This targeted biochemical inhibition reduces cellular oxidative stress, blocks ferroptosis, and suppresses tissue inflammation, providing therapeutic relevance in studied clinical conditions such as alcoholic hepatitis and chronic obstructive pulmonary disease.

Appendix RUO and cGMP Quality Standards

Quality Dimension RUO (Research Use Only) cGMP (Current Good Manufacturing Practice)
Clinical Applicability Prohibited in human clinical trials or medical diagnostics. Mandatory for human clinical trials (Phase I–III) and therapies.
Regulatory Status Non-regulated grade; exempt from drug manufacturing laws. Legally enforced by health authorities (e.g., FDA, EMA, NMPA).
Facility Environment Unclassified analytical or research laboratories. Validated Cleanrooms (ISO Class 5–8) with continuous monitoring.
Quality Control Basic purity and activity testing. Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma).
Process Validation Basic equipment calibration; no process validation required. Full qualification (IQ/OQ/PQ) and complete batch records.
Quality Assurance Vendor self-declared without required formal QMS. Mandatory QA/QC unit, Change Control, CAPA, and vendor audits.
Regulatory Impact High risk of IND rejection if used as a critical raw material. Required for IND/NDA filings, supported by Drug Master Files (DMF).

Footnotes

Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).

Note: Technical data last updated: Sep 1, 2026.