CAS No. 537-55-3

Batch: Purity:99.53
N-Acetyl-L-tyrosine Chemical Structure
Chemical Structure
Check the N-Acetyl-L-tyrosine product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 537-55-3
Molecular Formula

C11H13NO4

Molecular Weight (MW) 223.23
SMILES CC(=O)NC(CC1=CC=C(C=C1)O)C(=O)O

Biological Activity

N-Acetyl-L-tyrosine is an acetylated form and water-soluble derivative of L-tyrosine that functions as a metabolic precursor in neurotransmitter biosynthesis. Following enzymatic conversion to L-tyrosine, it supports the catecholamine production pathway, contributing to the synthesis of dopamine, norepinephrine, and epinephrine. This pathway is essential for regulating central nervous system signaling, cognitive processes, and physiological stress responses. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 45 mg/mL (201.58 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Reference

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Note: Technical data last updated: Sep 1, 2026.