CAS No. 2901-75-9

Batch: Purity:99.96
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Afalanine (N-Acetyl-DL-phenylalanine) Chemical Structure
Chemical Structure
Check the Afalanine (N-Acetyl-DL-phenylalanine) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 2901-75-9
Molecular Formula

C11H13NO3
Molecular Weight (MW) 207.23
SMILES CC(=O)NC(CC1=CC=CC=C1)C(=O)O

Ordering Information

Biological Activity

Afalanine (N-Acetyl-DL-phenylalanine) acts as an antidepressant agent and an endogenous amino acid metabolite. As an N-acetylated derivative of phenylalanine, it plays a role in amino acid metabolic pathways and central nervous system regulation. The compound modulates metabolic processing associated with catecholamine biosynthesis and monoaminergic signaling in the brain, contributing to its reported antidepressant activity and potential neurological effects in preclinical metabolic studies. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 41 mg/mL (197.84 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.