CAS No. 171485-39-5
Chemical Structure
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Myrislignan
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | 4-[(1R,2S)-2-(2,6-dimethoxy-4-prop-2-enylphenoxy)-1-hydroxypropyl]-2-methoxyphenol | |
|---|---|---|
| CAS Number | 171485-39-5 | |
| Molecular Formula |
C21H26O6 |
|
| Molecular Weight (MW) | 374.43 | |
| InChIKey | ULZFTGWWPHYLGI-RBZFPXEDSA-N |
Biological Activity
Myrislignan is a natural lignan isolated from Myristica fragrans Houtt that exhibits anti-inflammatory activity through inhibition of the NF-κB signaling pathway. Downstream of NF-κB pathway suppression, myrislignan dose-dependently reduces the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in lipopolysaccharide (LPS)-stimulated macrophage cells. Consequently, it inhibits the production and release of inflammatory cytokines, including interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α). [1]
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Note: Technical data last updated: Sep 1, 2026.