CAS No. 267402-71-1
Batch:
Purity:99.26
Chemical Structure
Check the
Myoseverin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 2-N,6-N-bis[(4-methoxyphenyl)methyl]-9-propan-2-ylpurine-2,6-diamine | |
|---|---|---|
| CAS Number | 267402-71-1 | |
| Molecular Formula |
C24H28N6O2 |
|
| Molecular Weight (MW) | 432.52 | |
| SMILES | CC(C)N1C=NC2=C(N=C(N=C21)NCC3=CC=C(C=C3)OC)NCC4=CC=C(C=C4)OC | |
| InChIKey | IDCOTQWQVPRTNK-UHFFFAOYSA-N |
Myoseverin is a microtubule-binding trisubstituted purine that directly binds tubulin and disrupts the structure of the microtubule cytoskeleton. By altering microtubule dynamics, myoseverin reversibly affects cellular function and induces myotube fission. This disruption impairs myotube maintenance, alters muscle-specific gene expression, and permits cleavage of multinucleated cells into mononucleated cells without inducing apoptotic cell death. [1]
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
87 mg/mL
(201.14 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 22 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.