Molecular Weight: 273.33 g/mol

MYK-461 (Mavacamten) Chemical Structure
Chemical Structure
Check the MYK-461 (Mavacamten) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 55 mg/mL (201.22 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 5 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Chemical Information

IUPAC Name 6-[[(1S)-1-phenylethyl]amino]-3-propan-2-yl-1H-pyrimidine-2,4-dione
CAS Number 1642288-47-8
Molecular Formula

C15H19N3O2
Molecular Weight (MW) 273.33
SMILES CC(C)N1C(=O)C=C(NC1=O)NC(C)C2=CC=CC=C2
InChIKey RLCLASQCAPXVLM-NSHDSACASA-N

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Note: Technical data last updated: Sep 1, 2026.