CAS No. 944547-46-0

Batch: Purity:99.75
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Mycro 3 Chemical Structure
Chemical Structure
Check the Mycro 3 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name ethyl 5-[[7-[chloro(difluoro)methyl]-5-(furan-2-yl)pyrazolo[1,5-a]pyrimidine-2-carbonyl]amino]-1-phenylpyrazole-4-carboxylate
CAS Number 944547-46-0
Molecular Formula

C24H17ClF2N6O4
Molecular Weight (MW) 526.88
SMILES CCOC(=O)C1=C(N(N=C1)C2=CC=CC=C2)NC(=O)C3=NN4C(=CC(=NC4=C3)C5=CC=CO5)C(F)(F)Cl
InChIKey YPPNLSKYXDXQGD-UHFFFAOYSA-N

Ordering Information

Biological Activity

Mycro 3 is a potent and selective inhibitor of the c-Myc transcription factor, exhibiting weak inhibitory activity against AP-1. By disrupting c-Myc dimerization, it suppresses c-Myc-mediated transcriptional activation and downregulates downstream target genes. Consequently, Mycro 3 inhibits cancer cell proliferation, blocks cell cycle progression, and induces apoptosis in c-Myc-dependent tumor models. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (189.79 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.