CAS No. 88671-89-0
Batch:
Purity:99.13
Chemical Structure
Check the
Myclobutanil
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | 2-(4-chlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)hexanenitrile | |
|---|---|---|
| CAS Number | 88671-89-0 | |
| Molecular Formula |
C15H17ClN4 |
|
| Molecular Weight (MW) | 288.78 | |
| SMILES | CCCCC(CN1C=NC=N1)(C#N)C2=CC=C(C=C2)Cl | |
| InChIKey | HZJKXKUJVSEEFU-UHFFFAOYSA-N |
Biological Activity
Myclobutanil is a broad-spectrum triazole fungicide that functions as a steroid demethylation inhibitor, specifically targeting fungal lanosterol 14α-demethylase (CYP51). By blocking CYP51 enzyme activity, myclobutanil effectively disrupts ergosterol biosynthesis, a vital pathway responsible for maintaining fungal cell membrane structure. This inhibition leads to compromised membrane integrity and increased permeability, ultimately suppressing fungal cell growth and survival. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
58 mg/mL
(200.84 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
Jump to
Note: Technical data last updated: Sep 1, 2026.