CAS No. 1314533-27-1

Batch: Purity:98.25
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MSDC-0602K Potassium Chemical Structure
Chemical Structure
Check the MSDC-0602K Potassium product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name potassium 5-[[4-[2-(3-methoxyphenyl)-2-oxoethoxy]phenyl]methyl]-1,3-thiazolidin-3-ide-2,4-dione
CAS Number 1314533-27-1
Molecular Formula

C19H16NO5S.K
Molecular Weight (MW) 409.5
SMILES [K+].COC1=CC=CC(=C1)C(=O)COC2=CC=C(CC3SC(=O)[N-]C3=O)C=C2
InChIKey PQCFIIIBRQVVGW-UHFFFAOYSA-M

Ordering Information

Biological Activity

MSDC-0602K is an insulin sensitizer that selectively modulates the mitochondrial pyruvate carrier (MPC). By blocking pyruvate entry into the mitochondria, it alters cellular energy metabolism, reduces hepatic gluconeogenesis, and enhances insulin sensitivity without displaying significant PPARγ agonist activity. This modulation attenuates metabolic dysfunction and alters downstream mitochondrial nutrient fluxes in cellular and animal models. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 82 mg/mL (200.24 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.