CAS No. 112885-41-3

Batch: Purity:98
Check CoA
Mosapride Chemical Structure
Chemical Structure
Check the Mosapride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 112885-41-3
Molecular Formula

C21H25ClFN3O3
Molecular Weight (MW) 421.89
SMILES CCOC1=CC(=C(C=C1C(=O)NCC2CN(CCO2)CC3=CC=C(C=C3)F)Cl)N

Biological Activity

Mosapride is a gastroprokinetic agent that acts as a selective serotonin 5-HT4 receptor agonist. Activation of 5-HT4 receptors by mosapride stimulates acetylcholine release from enteric cholinergic neurons, promoting gastrointestinal motility and enhancing gastric emptying. This mechanism facilitates upper gastrointestinal tract coordination without affecting central nervous system dopamine receptors or cardiac potassium channels.

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 84 mg/mL (199.1 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Jump to

Note: Technical data last updated: Sep 1, 2026.