CAS No. 62596-29-6

Batch: Purity:99.99
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Morusin Chemical Structure
Chemical Structure
Check the Morusin product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 2-(2,4-dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-3-(3-methylbut-2-enyl)pyrano[2,3-h]chromen-4-one
CAS Number 62596-29-6
Molecular Formula

C25H24O6
Molecular Weight (MW) 420.46
SMILES CC(=CCC1=C(OC2=C(C1=O)C(=CC3=C2C=CC(O3)(C)C)O)C4=C(C=C(C=C4)O)O)C
InChIKey XFFOMNJIDRDDLQ-UHFFFAOYSA-N

Biological Activity

Morusin is a prenylated flavonoid that functions as an inhibitor of NF-kB and STAT3 signaling pathways. By attenuating the activation of NF-kB and STAT3 cascades, it suppresses downstream transcription factors involved in tumor progression and inflammatory responses. These pathway modulations contribute to inhibited cellular proliferation, induction of apoptosis, and compromised survival in cancer cell lines alongside reported antioxidant and antibacterial activities.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 84 mg/mL (199.78 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 84 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.