CAS No. 131-70-4

Batch: Purity:99.96
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Monobutyl phthalate Chemical Structure
Chemical Structure
Check the Monobutyl phthalate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 131-70-4
Molecular Formula

C12H14O4
Molecular Weight (MW) 222.24
SMILES CCCCOC(=O)C1=CC=CC=C1C(=O)O

Ordering Information

Biological Activity

Monobutyl phthalate, an active metabolite of di(n-butyl)phthalate, acts as an endocrine-disrupting compound that modulates cellular signaling. It alters the expression of epithelial-mesenchymal transition (EMT)-related proteins, leading to changes in cell morphology and junctional integrity. Consequently, exposure to monobutyl phthalate enhances the migration and invasive capacity of MLTC-1 cells, contributing to reproductive toxicity and altered Leydig cell function.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 44 mg/mL (197.98 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 44 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.