CAS No. 502887-71-0
Batch:
Purity:99.74
Chemical Structure
Check the
MMP-9-IN-1
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | N-[4-(difluoromethoxy)phenyl]-2-[(6-oxo-4-propyl-1H-pyrimidin-2-yl)sulfanyl]acetamide | |
|---|---|---|
| CAS Number | 502887-71-0 | |
| Molecular Formula |
C16H17F2N3O3S |
|
| Molecular Weight (MW) | 369.39 | |
| SMILES | CCCC1=CC(=O)NC(=N1)SCC(=O)NC2=CC=C(C=C2)OC(F)F | |
| InChIKey | OLTRRVUORWPRGF-UHFFFAOYSA-N |
MMP-9-IN-1 is a selective inhibitor of matrix metalloproteinase-9 (MMP-9) that targets the hemopexin domain. By binding to this regulatory domain, it disrupts protein-protein interactions essential for MMP-9 dimerization and cellular localization. Inhibiting MMP-9 function blocks extracellular matrix degradation, thereby suppressing cellular migration and invasive phenotypes associated with microenvironmental remodeling in pathological processes. [1][2]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
74 mg/mL
(200.33 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.