CAS No. 1832576-25-6
Chemical Structure
Check the
MLT-985
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 1-[2-chloro-7-[(1S)-1-methoxyethyl]pyrazolo[1,5-a]pyrimidin-6-yl]-3-[5-chloro-6-(triazol-2-yl)-3-pyridinyl]urea | |
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| CAS Number | 1832576-25-6 | |
| Molecular Formula |
C17H15Cl2N9O2 |
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| Molecular Weight (MW) | 448.27 | |
| InChIKey | GBIASRXDYFFUED-VIFPVBQESA-N |
MLT-985 is a selective, orally active allosteric inhibitor targeting mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1). By blocking MALT1-dependent protease signaling, the compound impairs aberrant CARD11/BCL10/MALT1 complex assembly and inhibits downstream NF-kB pathway activation. Consequently, MLT-985 suppresses cellular proliferation and promotes apoptotic phenotypes in activated B-cell-like diffuse large B-cell lymphoma (ABC-DLBCL) models. [1]
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Note: Technical data last updated: Sep 1, 2026.