CAS No. 2579689-83-9
Batch:
Purity:99.68
Chemical Structure
Check the
ML339
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | N-[(1S,5R)-9-[2-(2-chloroanilino)-2-oxoethyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3,4,5-trimethoxybenzamide | |
|---|---|---|
| CAS Number | 2579689-83-9 | |
| Molecular Formula |
C26H32ClN3O5 |
|
| Molecular Weight (MW) | 502.00 | |
| InChIKey | SSPYAPRDKNCABY-YQQQUEKLSA-N |
ML339 is a potent and selective antagonist of CXCR6. It antagonizes CXCL16-induced β-arrestin recruitment and cAMP signaling through human CXCR6, while displaying no inhibitory activity against CXCR5, CXCR4, and CCR6. Blockade of the CXCL16/CXCR6 signaling axis modulates downstream intracellular pathways that drive cell proliferation and migration, providing a useful chemical tool for prostate cancer research.
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(199.2 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 13 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.