CAS No. 59122-46-2

Batch: Purity:98
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Misoprostol Chemical Structure
Chemical Structure
Check the Misoprostol product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name methyl 7-[(1R,2R,3R)-3-hydroxy-2-[(E)-4-hydroxy-4-methyloct-1-enyl]-5-oxocyclopentyl]heptanoate
CAS Number 59122-46-2
Molecular Formula

C22H38O5
Molecular Weight (MW) 382.54
SMILES CCCCC(C)(CC=CC1C(CC(=O)C1CCCCCCC(=O)OC)O)O
InChIKey OJLOPKGSLYJEMD-URPKTTJQSA-N

Ordering Information

Biological Activity

Misoprostol is a synthetic prostaglandin E1 analog that acts as an agonist of EP prostanoid receptors, including EP2, EP3, and EP4. Activation of EP receptors modulates adenylate cyclase activity and intracellular cAMP levels, triggering downstream signaling pathways that promote gastric mucosal protection via increased mucus and bicarbonate secretion. In reproductive tissues, misoprostol-induced signaling stimulates uterine smooth muscle contraction and cervical ripening, facilitating its use in spontaneous abortion models. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 76 mg/mL (198.67 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 35 mg/mL
Ethanol 10 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.