CAS No. 25905-77-5

Batch: Purity:98
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Minaprine dihydrochloride Chemical Structure
Chemical Structure
Check the Minaprine dihydrochloride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 4-methyl-N-(2-morpholin-4-ylethyl)-6-phenylpyridazin-3-amine
CAS Number 25905-77-5
Molecular Formula

C17H24Cl2N4O
Molecular Weight (MW) 371.3
SMILES CC1=CC(=NN=C1NCCN2CCOCC2)C3=CC=CC=C3
InChIKey LDMWSLGGVTVJPG-UHFFFAOYSA-N

Ordering Information

Biological Activity

Minaprine dihydrochloride is a novel psychotropic compound that acts as a reversible inhibitor of monoamine oxidase A (MAO-A) and weakly inhibits acetylcholinesterase. By inhibiting MAO-A activity, it modulates central monoaminergic neurotransmission, particularly enhancing serotonergic and dopaminergic signaling. Furthermore, its interaction with cholinergic mechanisms contributes to altered neurotransmitter homeostasis and associated central nervous system phenotypes. [1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 74 mg/mL (199.29 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 74 mg/mL
Ethanol 4 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.