Metoprine

For research use only.

Catalog No.S0854 Synonyms: BW 197U

CAS No. 7761-45-7

Metoprine (BW 197U), a diaminopyrimidine derivative, is a potent inhibitor of histamine N-methyltransferase (HMT) that crosses the blood-brain barrier and increases brain histamine levels. Metoprine is an antifolate and antitumor agent.

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Biological Activity

Description Metoprine (BW 197U), a diaminopyrimidine derivative, is a potent inhibitor of histamine N-methyltransferase (HMT) that crosses the blood-brain barrier and increases brain histamine levels. Metoprine is an antifolate and antitumor agent.

Protocol

References

Solubility (25°C)

Chemical Information

Molecular Weight
Formula
CAS No. 7761-45-7
Storage powder
in solvent
Synonyms BW 197U
Smiles CC1=C(C(=NC(=N1)N)N)C2=CC(=C(C=C2)Cl)Cl

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID