CAS No. 36592-77-5
Batch:
Purity:95.98
Chemical Structure
Check the
Metipranolol hydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 36592-77-5 | |
|---|---|---|
| Molecular Formula |
C17H27NO4.ClH |
|
| Molecular Weight (MW) | 345.86 |
Biological Activity
Metipranolol hydrochloride is a non-selective β-adrenoceptor antagonist that exhibits notable antioxidant activity through the inhibition of lipid peroxidation. By antagonizing β-adrenergic receptors, it effectively decreases aqueous humor production and lowers elevated intraocular pressure associated with glaucoma. Consequently, this compound serves as a valuable research tool for investigating ocular hemodynamics, adrenergic signaling pathways, and glaucoma pathogenesis.
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
69 mg/mL
(199.5 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 69 mg/mL |
| Ethanol | 69 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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Note: Technical data last updated: Sep 1, 2026.