CAS No. 112825-05-5
Chemical Structure
Check the
Methyllycaconitine citrate (MLA)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 112825-05-5 | |
|---|---|---|
| Molecular Formula |
C43H58N2O17 |
|
| Molecular Weight (MW) | 874.92 | |
| SMILES | CO[C@@H]1C(C(N(CC)C2)C3(O)[C@H]4OC)([C@@](C[C@@]5([H])[C@@H]6OC)([H])[C@@]6([H])[C@@]3(C[C@@H]5OC)O)[C@@]4([H])[C@@]2(COC(C7=C(N(C8=O)C(C[C@@H]8C)=O)C=CC=C7)=O)CC1.O=C(CC(C(O)=O)(O)CC(O)=O)O |
Biological Activity
Methyllycaconitine citrate (MLA) is a selective antagonist of the α7 neuronal nicotinic acetylcholine receptor (α7nAChR). By selectively blocking α7nAChR activation, it inhibits receptor-mediated calcium influx and downstream cholinergic signaling pathways. This blockade modulates neurotransmitter release and cellular plasticity, providing a useful biological probe for studying neurodegenerative conditions and cognitive impairment associated with Alzheimer's disease. [1]
How to Prepare Stock Solution?
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Concentration
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Solubility
Reference
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- Methyllycaconitine citrate (MLA) Solubility in DMSO
- Methyllycaconitine citrate (MLA) Stock Solution
- Methyllycaconitine citrate (MLA) Storage
- Methyllycaconitine citrate (MLA) Stability
- Methyllycaconitine citrate (MLA) Molecular Weight
- Methyllycaconitine citrate (MLA) SMILES
- Methyllycaconitine citrate (MLA) Chemical Structure (2D and 3D)
- Methyllycaconitine citrate (MLA) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.