CAS No. 103-26-4

Batch: Purity:99.99
Methyl cinnamate Chemical Structure
Chemical Structure
Check the Methyl cinnamate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name methyl (E)-3-phenylprop-2-enoate
CAS Number 103-26-4
Molecular Formula

C10H10O2

Molecular Weight (MW) 162.19
SMILES COC(=O)C=CC1=CC=CC=C1
InChIKey CCRCUPLGCSFEDV-BQYQJAHWSA-N

Ordering Information

Biological Activity

Methyl cinnamate is a natural flavor compound derived from Zanthoxylum armatum that possesses antimicrobial and tyrosinase inhibitory activities. It effectively inhibits adipocyte differentiation in 3T3-L1 preadipocytes via activation of the CaMKK2/AMPK signaling pathway. This pathway activation suppresses key adipogenic transcription factors and reduces intracellular lipid accumulation, highlighting its potential role in modulating adipogenesis and cellular metabolic processes.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 32 mg/mL (197.29 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.