CAS No. 119478-56-7
Batch:
Purity:99.97
Chemical Structure
Check the
Meropenem Trihydrate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 119478-56-7 | |
|---|---|---|
| Molecular Formula |
C17H25N3O5S.3H2O |
|
| Molecular Weight (MW) | 437.51 | |
| SMILES | CC1C2C(C(=O)N2C(=C1SC3CC(NC3)C(=O)N(C)C)C(=O)O)C(C)O.O.O.O |
Meropenem Trihydrate is a broad-spectrum carbapenem antibacterial agent that targets penicillin-binding proteins (PBPs). By binding to PBPs, particularly PBP 2 and PBP 3, it inhibits peptidoglycan cross-linking during bacterial cell wall synthesis. This disruption impairs cell wall integrity, resulting in cell lysis and potent bactericidal activity against a wide variety of Gram-positive and Gram-negative bacterial pathogens. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
87 mg/mL
(198.85 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 87 mg/mL |
| Ethanol | 4 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.